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Table 1 Numbers (%) of patients with increases, no change, or decreases from baseline in HDL-C at endpoint presented by treatment group

From: Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin

 

HDL-C increase and no change

 

Treatment Group

HDL-C increase

n (%)

No change

n (%)

HDL-C decrease

n (%)

PBO (n = 123)

64 (52.0)

4 (3.3)

55 (44.7)

FENO (n = 368)

309 (84.0)

8 (2.2)

51 (13.9)

EZE+FENO (n = 183)

163 (89.1)

3 (1.6)

17 (9.3)

EZE/SIMVA+FENO (n = 180)

161 (89.4)

3 (1.7)

16 (8.9)

  1. EZE = ezetimibe; FENO = fenofibrate; PBO = placebo; SIMVA = simvastatin