Relationships between lipid profiles and metabolic syndrome, insulin resistance and serum high molecular adiponectin in Japanese community-dwelling adults

Table 3 Multiple linear regression analysis of the lipid measures with the number of MetS components, HOMA-IR and serum HMW adiponectin of subjects categorized by sex

Characteristics	β(P-value)
	Number. of MetS components		HOMA-IR§		Serum HMW adiponectin
	Men	Women	Men	Women	Men	Women
	N = 614	N = 779	N = 614	N = 779	N = 614	N = 779
Triglycerides (mg/dL)	0.337 (<0.001)	0.266 (<0.001)	0.237 (<0.001)	0.231 (<0.001)	-0.232 (<0.001)	-0.237 (<0.001)
HDL cholesterol (mg/dL)	-0.193 (<0.001)	-0.121 (<0.001)	-0.175 (<0.001)	-0.122 (<0.001)	0.218 (<0.001)	0.329 (<0.001)
LDL cholesterol (mg/dL)	-0.021 (0.503)	0.051 (0.048)	0.091 (0.009)	0.107 (0.001)	-0.126 (0.001)	-0.176 (0.001)
Non-HDL cholesterol (mg/dL)	0.115 (<0.001)	0.134 (<0.001)	0.164 (<0.001)	0.158 (<0.001)	-0.188 (<0.001)	-0.227 (<0.001)
Total cholesterol/HDL cholesterol ratio	0.256 (<0.001)	0.201 (<0.001)	0.252 (<0.001)	0.198 (<0.001)	-0.295 (<0.001)	-0.362 (<0.001)
Triglycerides/HDL cholesterol ratio	0.354 (<0.001)	0.257 (<0.001)	0.258 (<0.001)	0.228 (<0.001)	-0.270 (<0.001)	-0.315 (<0.001)
LDL cholesterol/HDL cholesterol ratio	0.143 (<0.001)	0.148 (<0.001)	0.209 (<0.001)	0.174 (<0.001)	-0.265 (<0.001)	-0.352 (<0.001)

MetS, Metabolic syndrome; HOMA-IR, homeostasis model assessment of insulin resistance; HMW, high molecular weight; HDL, high-density lipoprotein; LDL, low-density lipoprotein. §HOMA-IR was calculated using the following formula; {fasting blood glucose (mg/dL) X immuno-reactive insulin (mU/mL)}/405. Adjusted for age were BMI, smoking status, alcohol consumption, SBP, DBP, and eGFR. Data for triglycerides, triglycerides/HDL cholesterol ratio, and HOMA-IR were skewed, and log-transformed for analysis.

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