Figure 2From: Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in miceMast cells in abdominal fat depots. The density of mast cells in epididymal, mesenteric, perinephric, and inguinal (subcutaneous) fat depots from control (+/?, n = 10, white bars) and ob/ob mice (n = 10, black bars) are shown (A-J). Leptin deficiency-induced obesity was accompanied by a divergent change in the density of mast cells in inguinal and epididymal adipose tissues (K-O). Photomicrograhs demonstrate mast cells (arrows) stained for chloroacetate esterase. CD117/c-kit protein expression in epididymal and inguinal fat depots from ob/ob and control mice are also shown (P, Q). Scale bars are 50 μm. ***P < 0.001.Back to article page