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Table 4 Effect of rutin (RT) and/or ascorbic acid (AA) on plasma level of creatinine in high-cholesterol diet (HCD) fed rats following 6 weeks of supplementation

From: Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats

Treatment

(in rat chow)

Creatinine (μmol/l)

 

Male

Female

Control

51.94 ± 12.59

35.59 ± 9.71

RT (0.2%)

49.76 ± 6.94

32.91 ± 14.13

AA (0.4%)

51.21 ± 4.52

35.21 ± 12.03

RT (0.1%) + AA (0.2%)

55.21 ± 2.98

44.77 ± 14.21

HCD (1% cholesterol + 0.5% cholic acid)

43.95 ± 6.53

36.35 ± 13.88

RT (0.2%) + HCD

54.12 ± 9.29

47.07 ± 16.54

AA (0.4%) + HCD

55.93 ± 20.93

42.10 ± 11.40

RT (0.1%) + AA (0.2%) + HCD

53.39 ± 12.84

37.12 ± 9.79

  1. Data were expressed as Mean ± S.D and analyzed using one-way ANOVA followed by Student Newman-Keuls method as post hoc test. Six rats were used in each group