Effects of flaxseed oil on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose level

Table 1 The membrane fatty acid composition of erythrocytes (% of total FA)

	50 μM flaxseed oil + 50 mM glucose	100 μM flaxseed oil + 50 mM glucose	200 μM flaxseed oil +50 mM glucose	glucose group (50 mM)	PBS(0.01 M)
C14:0	2.90 ± 0.3*	3.70 ± 0.5**	4.20 ± 0.7**	1.90 ± 0.2	6.80 ± 0.4^##
(Myristic acid)
C16:0 (Palmitic acid)	36.44 ± 1.8*	27.25 ± 2.9**	24.22 ± 1.9**	38.10 ± 2.7	19.70 ± 2.2^##
C17:0	0.61 ± 0.1	0.62 ± 0.2	0.67 ± 0.1	0.62 ± 0.1	0.64 ± 0.2
(Internal standard)
C18:0	19.16 ± 3.0*	14.81 ± 3.0**	10. 44 ± 3.3**	21.30 ± 3.9	5.50 ± 1.7^##
(Stearic acid)
C18:1	21.11 ± 2.2*	19.01 ± 4.1**	16.71 ± 2.9**	24.40 ± 2.4	14.40 ± 0.9^##
(Vaccenic acid)
C18:2	2.20 ± 0.3*	4.90 ± 0.6**	6.30 ± 0.8**	1.40 ± 0.2	9.60 ± 0.5^##
(Linoleic acid)
C22:0	0.97 ± 0.2*	1.29 ± 0.2**	2.00 ± 0.4**	0.90 ± 0.1	3.90 ± 0.3^##
(Behenic acid)
C22:5	0.77 ± 0.2*	1.40 ± 0.3**	1.90 ± 0.3**	0.70 ± 0.1	2.80 ± 0.2^##
(Docosapentaenoic acid)
C22:6	0.79 ± 0.1*	1.10 ± 0.1**	2.10 ± 0.1**	0.60 ± 0.1	3.20 ± 0.6^##
(Docosadienoic acid)
RBC fatty acids	18.29 ± 1.4*	20.10 ± 2.2**	27.89 ± 2.7**	17.04 ± 2.5	32.33 ± 3.1^##
total concentration
(pmol/mg Hb)

Note: Three concentrations of flax seed oil effect on fatty acid composition of membrane. ^*: P < 0.05, ^** and ^##: P < 0.01 are significantly different from 50 mM glucose group (n = 24).

ISSN: 1476-511X