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Table 1 Baseline clinical characteristics of study participatns

From: Efficacy of combination of Ezetimibe 10 mg and rosuvastatin 2.5 mg versus rosuvastatin 5 mg monotherapy for hypercholesterolemia in patients with type 2 diabetes

 

Rosuva/Eze 2.5/10 mg (n = 39)

Rosuvastatin 5 mg (n = 36)

P value

Age, years

66.3 ± 11.7

63.0 ± 13.0

0.210

Male gender, n (%)

24 (62)

16 (44)

0.138

BMI, kg/m2

25.1 ± 3.6

26.5 ± 4.5

0.143

Systolic blood pressure, mmHg

127.4 ± 14.9

126.7 ± 13.8

0.849

Diastolic blood pressure, mmHg

72.2 ± 10.8

72.9 ± 8.0

0.754

Waist circumference, cm

90.5 ± 11.8

93.1 ± 11.0

0.360

MetSyn, (%)

17 (50)

18 (58)

0.515

Prevalence CVD, n (%)

4 (10)

2 (6)

0.376

Prevalence CI, n (%)

4 (10)

4 (11)

0.598

Hypertension, n (%)

28 (72)

23 (64)

0.463

Diabetes therapy

   

 Oral hypoglycemic agent, n (%)

30 (77)

30 (83)

0.488

 sulfonylurea, n (%)

16 (41)

19 (53)

0.143

 pioglitazone, n (%)

17 (44)

15 (42)

0.866

 metformin, n (%)

14 (36)

15 (42)

0.608

 α-glucosidase inhibitor, n (%)

8 (21)

3 (12)

0.136

 dipeptidyl peptidase-4 inhibitor, n (%)

3 (8)

4 (11)

0.454

Aspartate aminotransferase, U/L

27.2 ± 12.5

21.9 ± 5.6

0.596

Alanine aminotranserase, U/L

28.2 ± 16.3

21.2 ± 9.8

0.216

Creatine kinase, IU/L

130 ± 87

118 ± 63

0.489

Creatinine, mg/dL

0.8 ± 0.3

0.7 ± 0.2

0.316

  1. Data are mean ± SD, n, or n (%). Rosuva Rosuvastatin, Eze Ezetimibe, BMI Body mass index, MetSyn Metabolic syndrome [diagnosed by the criteria in japan], CVD Cardiovascular disease, CI Cerebral infarction.
  2. P values are for differences between two groups at baseline.