Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats

Table 5 Hepatic transcript abundance in LZR and OZR rats fed CON, FLAX, FISH, or SDA diets for 12 weeks

Gene symbol	Gene name	Ref. Seq. #	Lean			Obese
			FLAX	FISH	SDA	CON	FLAX	FISH	SDA
Scd1	Stearoyl coenzyme A desaturase 1	NM_139192	1.58^a	1.25^a	0.43^a	8.80^b	10.10^b	1.49^a	7.27^b
Fads1	Fatty acid desaturase 1 (Δ5 desaturase)	NM_053445	4.92^b	2.14^a	0.95^a	3.49^b	3.58^b	3.03^ab	2.43^ab
Fads2	Fatty acid desaturase 2 (Δ6 desaturase)	NM_031344	3.44^b	2.20^a	1.01^a	3.86^b	4.54^c	3.57^b	3.62^b
Elovl5	Elongation of very long chain fatty acids 5	NM_134382	4.41^b	1.81^a	0.96^a	2.81^ab	4.23^b	2.28^a	2.12^a
Elovl6	Elongation of very long chain fatty acids 6	NM_134383	1.94^b	0.75^a	0.45^a	17.39^c	50.01^d	11.17^c	22.84^c
Acox1	Acyl coenzyme A oxidase 1	NM_017340	1.54^a	1.48^a	2.23^ab	1.64^a	2.22^ab	2.45^b	2.54^b
PPARα	Peroxisome proliferator activated receptor α	NM_013196	2.38^a	1.04^a	1.00^a	4.14^b	4.81^b	4.56^b	3.94^b

Data are expressed as fold change relative to LZR rats fed control diet. Letters represent significance difference among treatments groups as determined by comparison of normalized Ct values (target Ct - housekeeping Ct) with paired t test.

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