Fatty acid ( % of total) | Lean | Obese | Main effect | Â | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 | CON | FLAX | FISH | SDA | CON | FLAX | FISH | SDA | Genotype | Diet | Interaction |
LA [18:2(n-6)] | 0.06 ± 0.02ac | 0.007 ± 0.02b | 0.02 ± 0.02abc | 0.04 ± 0.02abc | 0.03 ± 0.01ab | 0.02 ± 0.01ab | 0.03 ± 0.02ab | 0.07 ± 0.01c | P = 0.95 | P = 0.0045i | P = 0.64 |
ALA [18:3(n-3)] | 1.71 ± 0.64 | 4.79 ± 0.69 | 1.88 ± 0.67 | 4.08 ± 0.65 | 1.80 ± 0.69 | 3.51 ± 0.54 | 1.32 ± 0.66 | 1.80 ± 0.67 | P = 0.23 | P < 0.0001ii | P = 0.18 |
SDA [18:4(n-3)] | 0.66 ± 0.35 | 0.39 ± 0.38 | 0.47 ± 0.38 | 2.72 ± 0.36 | 0.044 ± 0.38 | 0.15 ± 0.30 | 0.19 ± 0.37 | 0.41 ± 0.37 | P = 0.067†| P < 0.0001i | ΔP = 0.0020 |
AA [20:4(n-6)] | 5.37 ± 0.64b | 3.40 ± 0.70a | 1.90 ± 0.68a | 3.58 ± 0.65a | 3.60 ± 0.70ab | 2.90 ± 0.54a | 3.74 ± 0.67ab | 3.63 ± 0.67ab | P = 0.91 | P = 0.026iii | ΔP = 0.019 |
EPA [20:5(n-3)] | 0.41 ± 0.21 | 0.48 ± 0.22 | 1.66 ± 0.22 | 1.41 ± 0.21 | 0.32 ± 0.22 | 0.22 ± 0.17 | 0.85 ± 0.21 | 1.11 ± 0.21 | P = 0.15 | P < 0.0001iv | P = 0.18 |
DPA [22:5(n-3)] | 1.19 ± 0.33 | 1.71 ± 0.36 | 1.69 ± 0.35 | 2.87 ± 0.34 | 0.99 ± 0.36 | 0.95 ± 0.28 | 1.51 ± 0.34 | 2.15 ± 0.35 | P = 0.28 | P < 0.0001i | P = 0.58 |
DHA [22:6(n-3)] | 4.14 ± 1.00ac | 4.82 ± 1.08ab | 7.09 ± 1.06b | 4.06 ± 1.01a | 2.27 ± 1.08a | 1.87 ± 0.84a | 3.57 ± 1.03ac | 5.01 ± 1.04c | P = 0.16 | P = 0.054iv | ΔP = 0.043 |
∑SFA | 29.69 ± 0.64 | 29.50 ± 0.70 | 31.17 ± 0.68 | 28.54 ± 0.65 | 30.12 ± 0.70 | 30.15 ± 0.54 | 32.38 ± 0.67 | 30.24 ± 0.68 | P = 0.24 | P = 0.0004v | P = 0.65 |
∑MUFA | 50.76 ± 2.26 | 51.57 ± 2.45 | 46.00 ± 2.39 | 46.86 ± 2.29 | 56.05 ± 2.45 | 50.83 ± 1.90 | 47.21 ± 2.34 | 42.56 ± 2.36 | P = 0.90 | P < 0.0001vi | P = 0.093 |
∑n3PUFA | 8.32 ± 1.52 | 12.29 ± 1.65 | 13.00 ± 1.61 | 15.63 ± 1.54 | 5.54 ± 1.65 | 6.79 ± 1.28 | 7.67 ± 1.57 | 10.88 ± 1.59 | P = 0.023†| P < 0.0001vii | P = 0.72 |
∑n6PUFA | 5.41 ± 0.65c | 3.41 ± 0.70b | 1.92 ± 0.69a | 3.62 ± 0.66b | 3.62 ± 0.70b | 2.91 ± 0.55ab | 3.76 ± 0.67b | 3.68 ± 0.68b | P = 0.91 | P = 0.026iii | ΔP = 0.020 |