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Table 3 Comparison of serum lipid levels among the genotypes in the Mulao and Han populations

From: Association of the ST3GAL4 rs11220462 polymorphism and serum lipid levels in the Mulao and Han populations

Genotype

n

TC

TG

HDL-C

LDL-C

ApoAI

ApoB

ApoAI/ApoB

  

(mmol/L)

(mmol/L)

(mmol/L)

(mmol/L)

(g/L)

(g/L)

 

Han

        

GG

253

5.00 ± 0.96

1.08 (1.07)

1.71 ± 0.55

2.85 ± 0.78

1.36 ± 0.29

0.87 ± 0.19

1.64 ± 0.53

AG

351

5.05 ± 0.92

1.05 (0.74)

1.77 ± 0.60

2.95 ± 0.81

1.35 ± 0.23

0.85 ± 0.18

1.65 ± 0.44

AA

90

5.10 ± 0.99

1.08 (1.09)

1.73 ± 0.43

2.96 ± 0.81

1.36 ± 0.30

0.85 ± 0.19

1.68 ± 0.50

F

-

0.519

4.963

1.041

0.309

0.121

0.391

0.437

P

-

0.595

0.084

0.353

0.734

0.886

0.676

0.646

Mulao

        

GG

286

4.80 ± 1.18

1.04 (0.84)

1.73 ± 0.41

2.82 ± 0.82

1.31 ± 0.41

0.89 ± 0.25

1.57 ± 0.70

AG

344

5.09 ± 1.01

1.10 (0.73)

1.77 ± 0.49

2.98 ± 0.83

1.33 ± 0.39

0.90 ± 0.53

1.58 ± 0.79

AA

76

5.17 ± 0.89

1.15 (0.77)

1.74 ± 0.41

3.09 ± 0.80

1.30 ± 0.42

0.98 ± 0.61

1.53 ± 0.64

F

-

7.378

1.784

0.910

5.405

0.056

0.587

0.086

P

-

0.001

0.410

0.403

0.005

0.946

0.556

0.918

Han/male

        

GG

120

5.00 ± 0.97

1.32 (1.18)

1.65 ± 0.42

2.90 ± 0.73

1.36 ± 0.32

0.91 ± 0.19

1.57 ± 0.58

AG

182

5.20 ± 0.73

1.09 (0.72)

1.73 ± 0.35

3.02 ± 0.68

1.37 ± 0.23

0.90 ± 0.15

1.57 ± 0.35

AA

29

5.41 ± 0.95

1.36 (0.47)

1.70 ± 0.69

3.04 ± 0.86

1.41 ± 0.39

0.89 ± 0.17

1.66 ± 0.58

F

-

7.255

12.933

1.734

1.422

2.147

0.736

1.304

P

-

0.001

0.002

0.178

0.243

0.118

0.480

0.273

Han/female

        

GG

134

4.99 ± 0.96

0.96 (0.38)

1.80 ± 0.43

2.88 ± 0.83

1.35 ± 0.25

0.83 ± 0.17

1.70 ± 0.48

AG

182

4.90 ± 1.05

0.98 (0.79)

1.81 ± 0.76

2.88 ± 0.91

1.32 ± 0.23

0.81 ± 0.20

1.73 ± 0.51

AA

47

4.80 ± 0.94

1.07 (0.59)

1.71 ± 0.38

2.88 ± 0.77

1.32 ± 0.18

0.81 ± 0.20

1.70 ± 0.40

F

-

1.215

3.999

0.648

0.113

0.305

1.166

0.973

P

-

0.298

0.135

0.524

0.894

0.737

0.313

0.379

Mulao/male

        

GG

130

4.77 ± 1.17

1.04 (1.05)

1.75 ± 0.44

2.72 ± 0.82

1.31 ± 0.46

0.88 ± 0.17

1.59 ± 0.68

AG

167

5.04 ± 0.85

1.17 (1.05)

1.75 ± 0.57

2.96 ± 0.73

1.36 ± 0.39

0.90 ± 0.66

1.52 ± 0.69

AA

43

5.08 ± 0.84

1.15 (0.77)

1.66 ± 0.37

2.97 ± 0.81

1.23 ± 0.42

0.91 ± 0.47

1.42 ± 0.51

F

-

5.108

2.476

0.839

3.230

1.478

3.182

1.166

P

-

0.007

0.290

0.433

0.041

0.230

0.043

0.313

Mulao/female

        

GG

156

4.82 ± 1.18

1.04 (0.64)

1.72 ± 0.39

2.90 ± 0.82

1.32 ± 0.37

0.88 ± 0.35

1.56 ± 0.71

AG

177

5.03 ± 1.14

1.01 (0.66)

1.78 ± 0.41

3.00 ± 0.91

1.30 ± 0.38

0.93 ± 0.33

1.64 ± 0.87

AA

33

5.40 ± 0.92

1.04 (0.73)

1.84 ± 0.44

3.29 ± 0.89

1.39 ± 0.41

1.04 ± 0.70

1.68 ± 0.76

F

-

4.376

0.393

1.251

3.097

0.891

3.678

0.289

P

-

0.023

0.822

0.287

0.049

0.411

0.026

0.749

  1. TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, Apo lipoprotein AI; ApoB, Apo lipoprotein B. The association of genotypes and serum lipid parameters was tested by analysis of covariance (co-variables include sex, age, body mass index, blood pressure, alcohol consumption, cigarette smoking and blood glucose). The value of TG was presented as median (interquartile range), and their difference among the genotypes was determined the Wilcoxon-Mann–Whitney test.
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Lipids in Health and Disease

ISSN: 1476-511X