Figure 5
Photomicrographs of gastric mucosa (Hematoxylin-Eosin staining: magnification 20× for a, b, d, e, g, i, j and l; 40× for c, f, h, k and m). (a) micrograph of female rats pretreated with HCI/ethanol (ulcer control group), there is epithelial exfoliation and extensive edema (ede) of submucosa layer with distorted glands; (b, c) micrograph of male rats pretreated with HCI/ethanol (ulcer control group) shows discontinuity in the lining epithelium with exudates in the lumen submucosal edema (ede) of submucosa layer with distorted glands. (d) Omeprazole groups showing epithelium and submucosa with normal characteristics. The EOTa, at 54 mg kg −1(e, f), 117 mg kg-1 (g,h) and 180 mg kg−1(i) (for FR) showign mocosal regeneration with exudates in lumen with some inflammatory cells, mild mucosal damage, mild leukocyte infiltration, and mild submucosal edema. The EOTa, at 54 mg kg −1(j, k) and 117 mg kg −1(l) (for MR) showign clearly mucosal hemorrage, submucosal edema, leukocyte and neutrophil infiltration, inflammatory cell and abundant neutrophils, but The EOTa, at 180 mg kg −1(m) showing clearly moderate mucosal damage and moderate submucosal edema.