Postprandial enrichment of triacylglycerol-rich lipoproteins with omega-3 fatty acids: lack of an interaction with apolipoprotein E genotype?

Table 2 Fatty acid profiles of S _f >400 fractions in response to acute docosahexaenoic acid (DHA) intake in carriers ( E4 +) and non-carriers ( E4 −) of an APOE4 allele

		Fasting	Postprandial	Change	P values
		(relative%)	(relative%)	(Δ)	Interaction	Genotype	Time
16:0	E4+	33.44 ± 2.05	33.75 ± 0.77	+ 0.31	0.457	0.833	0.487
16:0	E4−	34.26 ± 1.49	33.76 ± 1.01	+ 0.50	0.457	0.833	0.487
18:0	E4+	23.75 ± 2.92	10.61 ± 1.65	− 13.14	0.482	0.310	<0.001
18:0	E4−	27.12 ± 1.73	9.74 ± 1.03	− 17.38	0.482	0.310	<0.001
16:1 n − 7	E4+	1.44 ± 0.18	0.44 ± 0.08	− 1.00	0.467	0.174	0.011
16:1 n − 7	E4−	1.46 ± 0.13	0.74 ± 0.20	− 0.72	0.467	0.174	0.011
18:1 n − 9	E4+	21.74 ± 4.21	33.70 ± 1.18	+ 11.96	0.708	0.969	<0.001
18:1 n − 9	E4−	22.51 ± 1.54	33.12 ± 0.72	− 10.61	0.708	0.969	<0.001
18:2 n − 6	E4+	8.63 ± 2.90	12.51 ± 0.68	+ 3.88	0.219	0.520	0.001
18:2 n − 6	E4−	5.69 ± 0.88	13.31 ± 1.05	+ 7.62	0.219	0.520	0.001
20:4 n − 6	E4+	0.78 ± 0.12	0.77 ± 0.08	− 0.01	0.547	0.265	0.757
20:4 n − 6	E4−	1.44 ± 0.65	0.98 ± 0.11	− 0.46	0.547	0.265	0.757
18:3 n − 3	E4+	2.68 ± 0.85	0.89 ± 0.08	− 1.79	0.196	0.309	0.015
18:3 n − 3	E4−	1.60 ± 0.37	0.93 ± 0.07	− 0.67	0.196	0.309	0.015
20:5 n − 3	E4+	1.52 ± 0.29	0.86 ± 0.10	− 0.66	0.081	0.251	0.154
20:5 n − 3	E4−	0.90 ± 0.21	0.86 ± 0.13	− 0.04	0.081	0.251	0.154
22:6 n − 3	E4+	1.50 ± 0.65	2.53 ± 0.48	+ 1.03	0.949	0.219	0.024
22:6 n − 3	E4−	0.75 ± 0.16	1.96 ± 0.45	+ 1.21	0.949	0.219	0.024

Values are presented as mean relative percentages ± SEM or as change (Δ) compared to fasted state (i.e.% at postprandial value –% at fasting value). P values were obtained using a Factorial Repeated Measures (Split-Plot) ANOVA in SPSS version 22.0 (IBM Corp., Armonk, NY). Bold characters are used to indicate significant effects (P < 0.05).

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