Postprandial enrichment of triacylglycerol-rich lipoproteins with omega-3 fatty acids: lack of an interaction with apolipoprotein E genotype?

Table 4 Fatty acid profiles of S _f 20 − 60 fractions in response to acute docosahexaenoic acid intake in carriers ( E4 +) and non-carriers ( E4 −) of an APOE4 allele

		Fasting	Postprandial	Change	P values
		(relative%)	(relative%)	(Δ,%)	*Interaction*	*Genotype*	*Time*
16:0	E4+	28.40 ± 1.07	29.71 ± 1.24	+ 1.31	0.535	0.330	0.193
16:0	E4−	27.69 ± 0.75	28.61 ± 0.80	+ 0.92	0.535	0.330	0.193
18:0	E4+	8.72 ± 0.53	7.12 ± 0.86	− 1.60	0.775	0.619	0.001
18:0	E4−	9.29 ± 0.67	7.28 ± 0.46	− 2.01	0.775	0.619	0.001
16:1 n − 7	E4+	2.49 ± 0.27	2.25 ± 0.26	− 0.24	0.630	0.921	<0.001
16:1 n − 7	E4−	2.60 ± 0.20	2.26 ± 0.18	− 0.34	0.630	0.921	<0.001
18:1 n − 9	E4+	29.79 ± 0.94	29.83 ± 1.17	+ 0.04	0.166	0.381	0.148
18:1 n − 9	E4−	28.01 ± 0.92	29.45 ± 0.43	+ 1.44	0.166	0.381	0.148
18:2 n − 6	E4+	17.12 ± 0.85	17.69 ± 0.47	+ 0.57	0.552	0.259	0.164
18:2 n − 6	E4−	17.84 ± 0.55	17.96 ± 0.49	+ 0.12	0.552	0.259	0.164
20:4 n − 6	E4+	2.22 ± 0.16	2.39 ± 0.18	+ 0.17	0.488	0.022	0.681
20:4 n − 6	E4−	2.91 ± 0.23	2.77 ± 0.19	− 0.14	0.488	0.022	0.681
18:3 n − 3	E4+	1.31 ± 0.16	1.19 ± 0.09	− 0.12	0.367	0.755	0.025
18:3 n − 3	E4−	1.35 ± 0.12	1.07 ± 0.05	− 0.28	0.367	0.755	0.025
20:5 n − 3	E4+	1.42 ± 0.17	1.24 ± 0.11	− 0.18	0.746	0.991	0.133
20:5 n − 3	E4−	1.39 ± 0.16	1.25 ± 0.11	− 1.14	0.746	0.991	0.133
22:6 n − 3	E4+	3.74 ± 0.53	3.77 ± 0.38	+ 0.03	0.779	0.706	0.896
22:6 n − 3	E4−	4.08 ± 0.46	3.82 ± 0.52	− 0.26	0.779	0.706	0.896

Values are presented as mean relative percentages ± SEM or as change (Δ) compared to fasted state (i.e.% at postprandial value –% at fasting value). P values were obtained using a Factorial Repeated Measures (Split-Plot) ANOVA in SPSS version 22.0 (IBM Corp., Armonk, NY). Bold characters are used to indicate significant effects (P < 0.05).

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