Figure 4

Comparison of neointimal area, intima/media ratio, lumen area and total vessel area between groups. a. Atherogenic diet and balloon angioplasty induced significant intimal hyperplasia in hyperlipidaemic rabbits: a P = non significant, Tamhane’s post hoc ANOVA analysis vs Group B; b P < 0.001, Tamhane’s post hoc ANOVA analysis vs control; c P < 0.05, Tamhane’s post hoc ANOVA analysis vs control. b. A significant increase in intima/media ratio was observed in angioplasty induced atherosclerotic lesions: d P < 0.05, Tamhane’s post hoc ANOVA analysis vs Group A; e P < 0.001, Tamhane’s post hoc ANOVA analysis vs Control; f P < 0.001, Tamhane’s post hoc ANOVA analysis vs Group A. c. Angioplasty resulted in a significant reduction in lumen of injured thoracic aortas: j P = 0.05, Tamhane’s post hoc ANOVA analysis vs Group B; k P < 0.001, Tamhane’s post hoc ANOVA analysis vs control; l P = non significant, Tamhane’s post hoc ANOVA analysis vs control. d. Injured thoracic aortas demonstrated a significant decrease in total vessel area consistent with constrictive remodeling occurrence: g P < 0.05, Bonferroni’s post hoc ANOVA analysis vs Group B; h P = non significant, Bonferroni’s post hoc ANOVA analysis vs control; i P = non significant, Bonferroni’s post hoc ANOVA analysis vs control.