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Table 7 Relative risks (RR) and 95% confidence intervals (95% CI) for the presence of a risk factor for cardiovascular disease in the entire cohort (only untreated patients)

From: Risk stratification of patients with familial hypercholesterolemia in a multi-ethnic cohort

 

Univariate

Multivariate (n = 295)

 

RR

95% CI

P value

RR

95% CI

P value

Diabetes (present vs. absent)

3.8

2.0-7.1

<0.001

3.8

2.0-7.5

<0.001

Male sex

2.7

1.7-4.3

<0.001

1.9

1.1-3.2

0.018

Lp (a) (high vs. low)*

-

-

-

-

-

-

HDL-C (mmol L-1)

0.2

0.1-0.4

<0.001

0.3

0.1-0.7

0.008

Family history pre-mature CVD

-

-

-

-

-

-

LDL-C (mmol L-1)

0.8

0.7-0.9

0.001

0.8

0.6-0.9

0.002

Smoking (ever vs. never)

1.8

1.1-2.9

0.014

-

-

-

  1. *:Lp (a) analysis carried out on the 199 untreated FH patients with Lp (a) data available.