Gene-diet interactions with polymorphisms of the MGLL gene on plasma low-density lipoprotein cholesterol and size following an omega-3 polyunsaturated fatty acid supplementation: a clinical trial

Ouellette, Catherine; Rudkowska, Iwona; Lemieux, Simone; Lamarche, Benoit; Couture, Patrick; Vohl, Marie-Claude

doi:10.1186/1476-511X-13-86

Lipids in Health and Disease

Table 3 Selected SNPs of the MGLL gene

From: Gene-diet interactions with polymorphisms of the MGLL gene on plasma low-density lipoprotein cholesterol and size following an omega-3 polyunsaturated fatty acid supplementation: a clinical trial

dbSNP	Sequence	MAF^1–2	Genotype/Frequency
rs782440	ACCAGC[C/T]TGTGCA	0.50	C/C (n = 53)	C/T (n = 105)	T/T (n = 52)
rs782440	ACCAGC[C/T]TGTGCA	0.50	0.25	0.50	0.25
rs16826716	GTTTCC[C/T]GTCATG	0.09	C/C (n = 172)	C/T (n = 38)	T/T (n = 0)
rs16826716	GTTTCC[C/T]GTCATG	0.09	0.82	0.18	0.00
rs6776142	CTGTCA[C/T]GCAGAG	0.33	C/C (n = 91)	C/T (n = 98)	T/T (n = 21)
rs6776142	CTGTCA[C/T]GCAGAG	0.33	0.43	0.47	0.10
rs9877819	ATACAC[A/G]AGGTGT	0.17	G/G (n = 145)	A/G (n = 59)	A/A (n = 6)
rs9877819	ATACAC[A/G]AGGTGT	0.17	0.69	0.28	0.03
rs555183	AGAGGC[A/G]CCATCA	0.43	A/A (n = 70)	A/G (n = 101)	G/G (n = 39)
rs555183	AGAGGC[A/G]CCATCA	0.43	0.33	0.48	0.19
rs6780384	CCTGGG[G/T]AGAAAG	0.10	G/G (n = 168)	G/T (n = 40)	T/T (n = 2)
rs6780384	CCTGGG[G/T]AGAAAG	0.10	0.80	0.19	0.01
rs13076593	TCCAAG[C/G]TAGTAA	0.12	C/C (n = 163)	C/G (n = 44)	G/G (n = 3)
rs13076593	TCCAAG[C/G]TAGTAA	0.12	0.78	0.21	0.01
rs605188	TCTGGG[C/T]GTCTGG	0.42	C/C (n = 72)	C/T (n = 98)	T/T (n = 40)
rs605188	TCTGGG[C/T]GTCTGG	0.42	0.34	0.47	0.19
rs6765071	CATGAC[C/T]ACGTTC	0.23	C/C (n = 126)	C/T (n = 73)	T/T (n = 44)
rs6765071	CATGAC[C/T]ACGTTC	0.23	0.60	0.35	0.21
rs782444	GGGCCA[C/T]AGGCAG	0.43	C/C (n = 72)	C/T (n = 94)	T/T (n = 44)
rs782444	GGGCCA[C/T]AGGCAG	0.43	0.34	0.45	0.21
rs549662	TGCGGT[A/G]AGTGTG	0.17	A/A (n = 145)	A/G (n = 59)	G/G (n = 6)
rs549662	TGCGGT[A/G]AGTGTG	0.17	0.69	0.28	0.03
rs3773155	CCCCCA[A/G]TCGCAC	0.12	A/A (n = 161)	A/G (n = 46)	G/G (n = 3)
rs3773155	CCCCCA[A/G]TCGCAC	0.12	0.77	0.22	0.01
rs541855	GTGAGA[C/T]GAAAGG	0.18	C/C (n = 139)	C/T (n = 65)	T/T (n = 6)
rs541855	GTGAGA[C/T]GAAAGG	0.18	0.66	0.31	0.03
rs6439081	ATGCCA[C/T]CACATG	0.24	T/T (n = 121)	C/T (n = 78)	C/C (n = 11)
rs6439081	ATGCCA[C/T]CACATG	0.24	0.58	0.37	0.05
rs6439082	CATCCC[C/T]GATCAG	0.15	C/C (n = 154)	C/T (n = 49)	T/T (n = 7)
rs6439082	CATCCC[C/T]GATCAG	0.15	0.73	0.23	0.03
rs6787155	CGGACA[A/C]GGTTTA	0.22	A/A (n = 130)	A/C (n = 66)	C/C (n = 14)
rs6787155	CGGACA[A/C]GGTTTA	0.22	0.62	0.31	0.07
rs1466571	CCAGGT[A/G]AAGAGA	0.33	G/G (n = 91)	A/G (n = 98)	A/A (n = 21)
rs1466571	CCAGGT[A/G]AAGAGA	0.33	0.43	0.47	0.10
rs893294	TGAGGA[A/T]GGATGG	0.34	A/A (n = 93)	A/T (n = 91)	T/T (n = 26)
rs893294	TGAGGA[A/T]GGATGG	0.34	0.44	0.43	0.12

¹Minor allele frequency.
²Allelic and genotypic frequencies were obtained using the ALLELE procedure in SAS Genetics V9.3.

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