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Table 3 Lipids and intracellular nutrient trafficking1 in perirenal fat and skeletal muscles in wild-type and hLPL rabbits

From: Unusual metabolic characteristics in skeletal muscles of transgenic rabbits for human lipoprotein lipase

 

Wild-type rabbits

hLPL rabbits

Perirenal fat

  

   Lipids

677 ± 25

691 ± 31

   GLUT4

198 ± 18

248 ± 30

Semimembranosus proprius muscle

  

   Lipids

46.5 ± 4.8

42.9 ± 6.5

   H-FABP

222 ± 19

*289 ± 20

   GLUT4

96.8 ± 14.9

†131.4 ± 8.5

Longissimus muscle

  

   Lipids

13.1 ± 2.3

11.8 ± 1.3

   H-FABP

20.4 ± 4.6

32.0 ± 6.0

   GLUT4

76.3 ± 11.8

94.4 ± 12.2

  1. 1Data are presented as mean + SEM in perirenal fat, semimembranosus proprius (SMP) and longissimus (LL) muscles. Abbreviation used: au (arbitrary units).
  2. *Difference in heart-fatty acid bind protein content (H-FABP) in hLPL rabbits as compared with wild-type littermates (P < 0.05).
  3. †Difference in insulin-sensitive glucose transporter GLUT4 in hLPL rabbits as compared with wild-type littermates (P < 0.10).