Figure 6
From: L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin
Effect of histidine analogs on LPLD activity A.) Chemical structure of histidine analogs compared. B.) Histidine analogs (15 mM) were added to the LPLD assay and analyzed for their effect on LPLD activity with (white bars) or without (black bars) addition of 1.0 mM Zn++. Results are shown as Mean ± SEM. Means, for each histidine analog vs. appropriate untreated control, were analyzed utilizing ANOVA/Tukey's post-test (GraphPad Prism, San Diego, CA): * (p < 0.001), ** (p < 0.01).