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Figure 2 | Lipids in Health and Disease

Figure 2

From: Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism

Figure 2

Total cholesterol efflux from bile (2a) and feces (2b) collected from control and P-glycoprotein deficient mice (Mdr1a/-/-/1b-/-) fed normal fat and high fat diets (Mdr1a/-/-/1b-/- genotype is designated "MDR" in all graphs; FVB wild type mouse is designated "WT"). No significant differences in total cholesterol in the bile were observed (n = 8; p > 0.05). However, the Mdr1a/-/-/1b-/- genotype was associated with a significant increase in fecal cholesterol concentration (n = 7; p < 0.05). Differing letter designations indicate statistically significant data.

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Lipids in Health and Disease

ISSN: 1476-511X