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Figure 5 | Lipids in Health and Disease

Figure 5

From: Novel point mutations attenuate autotaxin activity

Figure 5

H226Q does not inhibit the wild type migration response or hydrolytic activity. A. Migration: Values expressed as in Fig. 4. [WT-ATX] = 0.06 μg/ml; [H226Q-ATX] = 0.46 μg/ml, as indicated. *: p < .001 compared to no attractant. B. LPC Hydrolysis: Values (mean ± SEM) expressed as % WT-ATX. [WT-ATX] = 10 ng/reaction, [H226Q-ATX] = 40 ng/reaction, [LPC, 18:1] = 100 μM.

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Lipids in Health and Disease

ISSN: 1476-511X