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Table 2 Body and Heart Parameters

From: ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin

 

WILD TYPE

ADIPONECTIN-/-

 

SHAM

TAC

SHAM

TAC

 

STD

ω-3 PUFA

STD

ω-3 PUFA

STD

ω-3 PUFA

STD

ω-3 PUFA

Baseline body mass (g)

23.2 ± 0.4

22.9 ± 0.3

22.9 ± 0.3

23.6 ± 0.3

21.7 ± 0.4

21.7 ± 0.5

21.5 ± 0.3

22.2 ± 0.5

Terminal body mass (g)

28.0 ± 0.6

27.6 ± 0.5

26.1 ± 0.1

25.8 ± 1.1

26.6 ± 0.8

25.5 ± 0.6

26.5 ± 0.7

26.9 ± 0.6

Tibia length (mm)

19.4 ± 0.2

19.7 ± 0.3

19.2 ± 0.2

19.6 ± 0.2

18.9 ± 0.3

18.5 ± 0.2

18.7 ± 0.2

19.1 ± 0.3

Atrial mass/tibia length (mg·cm-1)

0.73 ± 0.07

0.50 ± 0.04

1.60 ± 0.29*

1.16 ± 0.13*

0.55 ± 0.06

0.76 ± 0.09

1.00 ± 0.09*

0.93 ± 0.13

Mean Diastolic Wall Thickness (μm)

76.5 ± 2.8

74.7 ± 3.7

80.9 ± 4.6

100.4 ± 3.6*#

79.8 ± 3.8

84.0 ± 3.6

114.8 ± 5.8*

109.1 ± 6.9*

Ejection Fraction (%)

50.9 ± 2.04

48.8 ± 3.5

25.9 ± 3.6*

22.9 ± 3.3*

51.5 ± 5.1

61.0 ± 3.0

46.5 ± 3.6

51.8 ± 3.5

Systolic Blood Pressure (mm Hg)

112 ± 3

105 ± 3

99 ± 2*

100 ± 3

120 ± 3

116 ± 3

112 ± 3

117 ± 3

Heart Rate (bpm)

597 ± 14

581 ± 15

637 ± 11*

616 ± 10

604 ± 13

577 ± 11

619 ± 11

610 ± 14

  1. Values are mean ± SEM; n = 12-15/group. *P < 0.05 vs. sham; # P < 0.05 vs. standard chow diet. TAC, transverse aortic constriction; STD, standard chow. Heart rate data were obtained in conscious mice during tail cuff blood pressure measurements.