Control group | HFD group | Acipimox group | |||||||
---|---|---|---|---|---|---|---|---|---|
Weeks | 8 w | 16 w | 24 w | 8 w | 16 w | 24 w | 8 w | 16 w | 24 w |
hepatic MDA (nmol/mg) | 1.59 ± 0.19 | 2.27 ± 0.30 | 2.41 ± 0.39 | 2.17 ± 0.21 | 5.65 ± 0.36**# | 7.15 ± 0.51**## | 2.01 ± 0.23 | 4.15 ± 0.28** | 3.62 ± 0.52 |
hepatic GSH-Px (U/mg) | 691.0 ± 31.2 | 674.1 ± 48.5 | 606.7 ± 36.2 | 471.5 ± 42.8* | 463.0 ± 26.9* | 504.4 ± 19.7 | 465.8 ± 56.4* | 514.8 ± 45.4* | 561.1 ± 54.6 |