Table 3 The content of major neurotransmitters and their metabolites in whole brain of 1st-litter neonatal female rats
Compound | Deficient | Control | Supplementary |
|---|---|---|---|
GABA (ug/g) | 273.2 ± 7.29** | 225.0 ± 7.9 | 220.7 ± 14.1 |
GLU (ug/g) | 604.8 ± 33.1 | 580.5 ± 56.2 | 550.7 ± 50.6 |
GLN (ug/g) | 264.7 ± 18.1** | 422.1 ± 32.4 | 788.5 ± 53.2** |
DA (ng/g) | 98.2 ± 10.8 | 106.4 ± 18.5 | 49.8 ± 4.5** |
DOPAC (ng/g) | 4848.6 ± 286.9** | 3797.4 ± 178.8 | 4407.3 ± 221.5* |
HVA (ng/g) | 11092.5 ± 963.5** | 7839.8 ± 908.1 | 9236.3 ± 988.0 |
NE (ng/g) | 2026.9 ± 409.7 | 2240.3 ± 323.5 | 1046.8 ± 106.5** |
MHPG (ng/g) | 2844.8 ± 185.3 | 2583.5 ± 245.3 | 2870.5 ± 225.2 |
VMA(ng/g) | 18152.5 ± 1482.2** | 24125.9 ± 1439.0 | 26581.2 ± 1395.4 |
TRY (ug/g) | 31.0 ± 1.9 | 30.8 ± 3.0 | 45.1 ± 3.4 |
5-HT (ng/g) | 215.9 ± 32.3 | 161.8 ± 20.9 | 169.2 ± 14.3 |
5-HIAA (ng/g) | 174.1 ± 19.2 | 223.8 ± 25.5 | 627.8 ± 41.7** |
5-HIAA/5-HT | 0.618 ± 0.1** | 1.745 ± 0.3 | 4.226 ± 0.6** |
KYN (ng/g) | 507.2 ± 49.8 | 487.2 ± 35.6 | 626.0 ± 26.8** |