Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population

Table 1 Basic characteristics of subjects in this study

	Total (n = 595)	Men (n = 312)	Women (n = 283)	P value
Age, yr	45.7 ± 10.2	44.9 ± 10.4	46.6 ± 10.0	0.047
Body mass index, kg/m²	24.3 ± 3.4	25.0 ± 3.1	23.5 ± 3.6	<0.001
Glucose (AC), mg/dL	97.2 ± 23.8	99.6 ± 26.4	94.5 ± 20.4	0.01
HDL-C, mg/dL	55.2 ± 14.3	49.7 ± 11.9	61.3 ± 14.2	<0.001
LDL-C, mg/dL	115.9 ± 33.0	118.4 ± 34.0	113.1 ± 31.6	0.051
Total cholesterol, mg/dL	198.5 ± 36.7	200.6 ± 37.3	196.2 ± 36.0	0.14
Triglyceride, mg/dL	142.5 ± 119.2	172.6 ± 147.9	109.3 ± 60.6	<0.001
CRP, mg/L	1.1 ± 1.4	1.1 ± 1.4	1.0 ± 1.4	0.131
Triglyceride/HDL-C ratio	3.01 ± 3.50	3.93 ± 4.42	2.00 ± 1.52	<0.001
SAA, mg/dL	5.4 ± 11.1	6.0 ± 13.3	4.7 ± 8.0	0.161
Fibrinogen, mg/dL	262.4 ± 68.1	260.3 ± 69.9	264.9 ± 66.0	0.405
sICAM1, μg/L	241.2 ± 112.2	243.7 ± 111.4	238.5 ± 113.2	0.579
sVCAM1, μg/L	492.2 ± 133.3	495.7 ± 150.9	488.2 ± 110.9	0.495
MMP2, mg/L	127.3 ± 40.8	124.2 ± 41.4	130.7 ± 40.0	0.056
MMP9, mg/L	142.6 ± 111.8	153.8 ± 115.5	130.2 ± 106.3	0.011
sE-selectin, μg/L	104.2 ± 51.9	117.5 ± 54.9	89.4 ± 44.0	<0.001
Diastolic BP, mmHg	75.0 ± 10.6	77.9 ± 10.4	73.6 ± 10.3	<0.001
Systolic BP, mmHg	114.8 ± 17.6	115.9 ± 16.4	113.7 ± 18.8	0.128
Current smokers, %	25	43.3	4.9	<0.001
Hypertension, %	11.8	15.1	8.1	0.006
Hypercholesterolemia, %	9.6	10.9	8.1	0.157
Diabetes mellitus, %	5	5.8	4.2	0.254

AC antecubital, BP blood pressure, CRP C-reactive protein, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, SAA serum amyloid A, sICAM1 soluble intercellular adhesive molecule 1, sVCAM1 soluble vascular cell adhesive molecule 1, MMP2 matrix metalloproteinase 2, MMP9 matrix metalloproteinase 9
Continuous variables are presented as mean ± SD. Triglyceride, HDL-C, LDL-C, total cholesterol, CRP, SAA, sICAM1, sVCAM1, sE-selectin, MMP2 and MMP9 values were logarithmically transformed before statistical testing to meet the assumption of normal distributions; however, the untransformed data are shown. BP levels and lipid variables were analyzed with the exclusion of the subjects using antihypertensive drugs and lipid lowering agents, respectively

ISSN: 1476-511X