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Table 8 Changes in weight and glucose metabolism related parameters of subjects after 12–14 weeks on placebo or α-CD either measured by conventional biochemistry methods or by NMR (mean ± SEM)

From: Randomized double blind clinical trial on the effect of oral α-cyclodextrin on serum lipids

Glucose metabolism

Placebo

α-CD

p

Weight (Kg)

74.8 ± 1.9

74.7 ± 2

0.99

Glucose (74–106 mg/dL)

88 ± 0.9

87 ± 0.7

0.05a

Insulin (2.6 − 24.9 mcU/mL)

7.1 ± 0.5

7.3 ± 0.6

0.56

Hgb A1C (4.0 − 6.0 %)

5.3 ± 0.4

5.3 ± 0.4

0.46

LIRIa (%, by NMR)

1.6 ± 0.1

1.4 ± 0.1

0.04a

HOMA IR index

1.6 ± 0.1

1.5 ± 0.1

0.15

  1. aLipoprotein Insulin Resistance Index [25]