Variables | Control group (n = 94) | SHO (n = 91) | HO (n = 73) |
p-value |
---|
Sex, M/F | 10/84 | 9/82 | 8/65 | 0.973 |
Age, years | 46.78 ± 11.22 | 45.96 ± 13.97 | 43.07 ± 13.55 | 0.077 |
BMI, km/m2
| 24.15 ± 3.25 | 24.57 ± 3.31 | 24.63 ± 3.19 | 0.990 |
CHOL, mmol/l | 5.00 ± 1.00 | 5.09 ± 1.21 | 5.98 ± 1.67†‡ | <0.001** |
HDL-C, mmol/l | 1.47 ± 0.30 | 1.47 ± 0.33 | 1.62 ± 0.40†‡ | 0.027* |
LDL-C, mmol/l | 2.89 ± 0.81 | 3.03 ± 0.95 | 3.47 ± 1.21†‡ | 0.001** |
TG, mmol/l | 1.12 (0.79–1.69) | 1.16 (0.78–1.78) | 1.28 (0.88–1.76) | 0.708 |
Apo A-I, g/l | 1.35 ± 0.27 | 1.34 ± 0.28 | 1.49 ± 0.38†‡ | 0.005** |
Apo B, g/l | 0.89 ± 0.24 | 0.92 ± 0.26 | 1.01 ± 0.34†‡ | 0.007** |
Hcy, μmol/l | 13.00 (10.75–15.00) | 14.00 (12.00–17.00)† | 15.00 (13.00–21.50)†‡ | <0.001** |
- Summary of the clinical characteristics and laboratory test results of the study participants (94 controls, 91 patients with SHO and 73 patients with HO). The data are expressed as means ± SDs unless otherwise indicated. TG and Hcy levels are presented as medians (25th and 75th percentiles). BMI body mass index, CHOL total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglycerides, Apo A-I apolipoprotein A-I, Apo B apolipoprotein B, Hcy homocysteine. Comparisons among groups were performed using aone-way ANOVA test. Because TG and Hcy levels did not follow a normal distribution, comparisons between groups were performed using the Mann–Whitney U test or Kruskal–Wallis H test. *p < 0.05, **p < 0.01, significantly different among the three groups; †p < 0.05, significantly different compared with the control group; ‡p < 0.05, significantly different compared with the SHO group