| Lowest tertile (n = 293) | Mid tertile (n = 296) | Highest tertile (n = 299) | P value |
---|---|---|---|---|
Age (year) | 65.4 ± 8.6 | 64.2 ± 9.3 | 62.0 ± 10.2*†| <0.001 |
Male (%) | 180 (61.4) | 172 (58.1) | 171 (57.2) | 0.295 |
Duration of diabetes (year) | 12.3 ± 9.3 | 12.2 ± 9.6 | 11.8 ± 9.3 | 0.779 |
BMI (kg/m2) | 23.2 ± 3.1 | 24.6 ± 3.0* | 24.9 ± 3.3* | <0.001 |
WC (cm) | 85.6 ± 8.5 | 89.8 ± 11.3* | 89.8 ± 8.5* | 0.005 |
WHR (cm) | 0.9 ± 0.1 | 0.9 ± 0.1 | 1.0 ± 0.1* | 0.010 |
SBP (mmHg) | 123.7 ± 14.5 | 126.6 ± 13.3 | 127.0 ± 15.8* | 0.016 |
DBP (mmHg) | 73.2 ± 9.7 | 74.8 ± 9.5 | 77.0 ± 9.7*†| <0.001 |
TyG index | 8.2 ± 0.3 | 8.9 ± 0.2* | 9.7 ± 0.4*†| <0.001 |
HOMA-IR | 2.1 (1.3–3.7) | 3.9 (2.1–7.1) * | 5.2 (3.2–10.1) *†| <0.001 |
FPG (mg/dL) | 117.1 ± 28.8 | 138.8 ± 31.6* | 188.4 ± 71.1*†| <0.001 |
PPG (mg/dL) | 185.6 ± 65.8 | 205.6 ± 76.0* | 245.6 ± 83.6*†| <0.001 |
HbA1c (%) | 7.4 ± 1.8 | 7.7 ± 1.9 | 8.8 ± 2.0*†| <0.001 |
Total cholesterol (mg/dL) | 155.5 ± 30.7 | 165.9 ± 32.8* | 182.9 ± 42.5*†| <0.001 |
Triglyceride (mg/dL) | 68 (54–83) | 115 (94–138)* | 188 (145–253) *†| <0.001 |
HDL cholesterol (mg/dL) | 52.0 ± 13.4 | 46.5 ± 10.2* | 44.2 ± 10.4* | <0.001 |
LDL cholesterol (mg/dL) | 89.9 ± 27.4 | 96.1 ± 29.7 | 97.4 ± 37.7* | 0.009 |
Estimated GFR (mL/min/1.73 m2) | 95.7 ± 24.6 | 93.8 ± 25.1 | 93.1 ± 24.2 | 0.125 |
Uric acid (mg/dL) | 4.9 ± 1.3 | 5.0 ± 1.4 | 5.2 ± 1.6 | 0.046 |
Insulin, n (%) | 59 (20.1) | 66 (22.3) | 83 (27.8) | 0.028 |
Sulfonylurea, n (%) | 117 (39.9) | 127 (42.9) | 109 (36.5) | 0.383 |
Meglitinide, n (%) | 39 (13.3) | 33 (11.1) | 35 (11.7) | 0.551 |
Metformin, n (%) | 161 (54.9) | 193 (65.3) | 202 (67.6) | 0.002 |
Thiazolidinedione, n (%) | 8 (2.7) | 8 (2.7) | 12 (4.0) | 0.370 |
α-glucosidase inhibitor, n (%) | 69 (23.5) | 63 (21.3) | 36 (12.0) | <0.001 |
DPP-IV inhibitor, n (%) | 19 (6.5) | 25 (8.4) | 22 (7.4) | 0.689 |
Antiplatelet agent, n (%) | 192 (66.2) | 173 (58.6) | 153 (51.7) | <0.001 |
Statin, n (%) | 151 (51.5) | 176 (59.5) | 138 (53.8) | 0.580 |