The effect of marine n-3 polyunsaturated fatty acids on cardiac autonomic and hemodynamic function in patients with psoriatic arthritis: a randomised, double-blind, placebo-controlled trial

Table 5 Per-protocol analysis

	Estimated effect (95% CI)	F statistic	P	N
RR ms	35.26 (3.00 to 67.53)	4.70	0.03	114
PNN50 %	1.81 (−3.99 to 7.61)	0.38	0.54	114
SDNN ms	−0.05 (−9.49 to 9.39)	0.00	0.99	114
RMSSD ms	1.35 (−9.06 to 11.76)	0.07	0.80	114
Peripheral systolic BP, mmHg	−1.48 (−6.25 to 3.29)	0.38	0.54	117
Peripheral diastolic BP, mmHg	0.26 (−2.45 to 2.96)	0.03	0.85	117
Pulse Wave Velocity, m/s	−0.15 (−0.83 to 0.54)	0.18	0.67	111
Central systolic BP mmHg	−0.90 (−5.23 to 3.44)	0.17	0.68	117
Central diastolic BP mmHg	−1.57 (−4.94 to 1.79)	0.86	0.36	117
PWA AIx	2.91 (0.12 to 5.71)	4.26	0.04	117

ANCOVA analysis of differences in outcomes from baseline to 24 weeks comparing n-3 PUFA to control. Analysis are controlled for age, sex, smoking, diabetes mellitus, hypertension, blood pressure, hypercholesterolemia, NSAID treatment and Disease activity scores. N are numbers of patients
CI Confidence Interval, HRV Heart rate variability, BP Blood pressure, PWV Pulse wave velocity, AIx central Augmentation Index

ISSN: 1476-511X