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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium

Fig. 2

HDL containing ApoM promotes endothelial cell viability upon serum/GF deprivation. a MTT assay of HUVEC after 24 h (left) or 48 h (right) of incubation in serum/GF deprivation medium with or without HDL+ApoM 50 μg/ml or HDL-ApoM 50 μg/ml. Data are expressed as mean ± SD. N = 4, one-way ANOVA p < 0.001 followed by Holm-Sidak method multiple-comparison post hoc test. b Cells were assayed as in a, but HDL+ApoM or HDL-ApoM concentrations were 50, 25 or 10 μg/ml. Data are expressed as mean ± SD. N = 4, one-way ANOVA p < 0.001 followed by Holm-Sidak method multiple-comparison post hoc test. * over the bars indicates statistical significance versus serum/GF deprivation treatment. *p < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X