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Table 3 Studies examining the effect of n-3 fatty acids as fish oils on CHD, stroke and total mortality

From: Docosahexaenoic acid regulates vascular endothelial cell function and prevents cardiovascular disease

Authors

Results of meta-analyses of population studies

Wang et al. (2006) [76]

↓ all-cause mortality; cardiac and sudden death

Bucher et al. (2002) [73]

↓ total mortality; cardiac and sudden death

He et al. (2004) [77]

↓ CHD mortality

Whelton et al. (2004) [75]

↓ fatal and total CHD

He et al. (2004) [77]

↓ stroke, particularly ischaemic stroke

Xun et al. (2012) [78]

↓ stroke, particularly ischaemic stroke

Authors

Results of randomised controlled trials

Burr et al. (1989) [79]

↓ all-cause mortality in post-MI patients

Valagussa et al. (1999) [80]

↓ total and cardiovascular mortality; sudden death in post-MI patients

Tavazzi et al. (2008) [82]

↓ total mortality and hospital admission for CVD in heart failure patients coronary events in patients with hypercholesterolaemia

Yokoyama et al. (2007) (81]

⇄ cardiovascular events in patients at high risk of CVD and impaired glucose or diabetes

Bosch et al. (2012) [83]

⇄ post-operative atrial fibrillation in patients undergoing cardiac surgery

Mozaffarian et al. (2012) [84]

⇄ cardiovascular mortality and morbidity in patients with multiple cardiovascular risk factors

  1. Abbreviations: CHD coronary heart disease, CVD cardiovascular disease.
  2. Adapted from reference [62] Mori et al. 2014