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Table 1 Classification of proteins located on the LD surface

From: Lipid Droplets in Health and Disease

Protein Group

Short Name

Long Name

References

PAT Family

PLIN

Perilipin

[49, 160]

ADRP

Adipose differentiation-related protein

[24, 27, 48, 161,162,163]

TIP47

Tail-interacting protein of 47 kD

[48, 160, 163,164,165]

Lipid & Energy Metabolism

HSL

Hormone sensitive lipase

[49, 160]

ATGL (PNPLA2)

Adipose triglyceride lipase

[24, 162, 166]

CGI-49

CGI-49 protein

[24, 27, 48, 49, 165]

CGI-58

CGI-58 protein

[24, 27, 49, 160, 162]

Mgll

Monoglyceride lipase

[97, 163]

Tgh

Triacylglycerol hydrolase

[167]

LACS3–4

Long-chain-fatty-acid–CoA ligase 3–4

[24, 48, 49, 162, 165]

H105e3

Sterol-4-carboxylate 3-dehydrogenase

[48, 163,164,165]

SE

Squalene monooxygenase

[27, 162, 168]

Lss

Lanosterol synthase

[49, 160, 169]

Cpla2

Cytosolic phospholipase A2

[24, 169, 170]

Pcyt1a

Phosphocholine cytidylyltransferase A

[169, 171, 172]

Mdh2

Malate dehydrogenase

[97, 173, 174]

Cyb5r3

NADH-cytochrome b5 reductase

[24, 49, 162, 173]

Dhrs1

Dehydrogenase/reductase SDR member 1

[24, 49, 162, 173]

Dhrs3

Short-chain dehydrogenase/reductase 3

[92, 169, 173]

Nsdhl

NAD(P)H steroid dehydrogenase-like

[163, 169, 173]

Acsl1–3

Long-chain acyl-CoA synthetase 1–3

[24, 49, 175]

Ldah

LD-associated hydrolase

[173, 176, 177]

Signalling

CHP

Calcium-binding protein p22

[24, 164, 165, 178]

Cav1

Caveolin1

[24, 49, 162]

METTL7A

Methyltransferase-like protein 7A

[92, 174, 178]

Membrane trafficking proteins

VIM

Vimentin

[24, 49, 160, 162, 171]

ACTB

Actin, cytoplasmic 1/ â–¡-Actin

[24, 27, 163, 165]

Rab10

Ras-related protein Rab-10

[24, 27, 48, 162, 165]

Rab 11A

Ras-related protein Rab-11A

[24, 162, 164]

Rab 1a

Ras-related protein Rab-1a

[24, 162, 164, 165]

Rab 1b

Ras-related protein Rab-1b

[48, 164, 165]

Rab 14

Ras-related protein Rab-14

[24, 49, 160, 162, 164]

Rab 18

Ras-related protein Rab-18

[24, 49, 162, 164, 165]

Rab 5b

Ras-related protein Rab-5b

[24, 162, 165, 166]

Tubulin

Tubulin

[24, 49, 163, 178]

Miscellaneous

Stomatin

Stomatin

[162, 165]

HSPA5

78 kDa glucose- regulated protein

[24, 48, 49, 160, 162,163,164,165]

Hspa1a

Heat shock 70 kDa protein 1A

[24, 49, 161]

FAF2

FAS-associated factor 2

[24, 48, 162, 166]

Ancient ubiquitous protein BiP

Ancient ubiquitous protein BiP

[24, 49, 160, 162, 165, 166]

CANX

Calnexin

[49]

HSP 70

Heat shock protein 70

[49, 161, 165]

Ribophorin I

Ribophorin I

[49, 160]

ApoB

Apolipoprotein B

[174]

a-synuclein

a-synuclein

[92]

Hepatitis C core protein

Hepatitis C core protein

[175,176,177]

His2A

Histone 2A

[89]

His2B

Histone 2B

[89]

Alb

Serum albumin

[27, 161, 163]