Table 3 Concentrations of EPA, DPA and DHA in the blood and tissues of Pten-knockout mice¹

blood

EPA

ND^2,a

4.05 ± 0.31^b

7.22 ± 0.28^c

10.1 ± 0.75^e

8.90 ± 0.37^d

ND^a

DPA

ND^a

1.54 ± 0.04^c

2.14 ± 0.07^d

2.57 ± 0.18^e

1.20 ± 0.04^b

ND^a

DHA

1.69 ± 0.11^b

5.50 ± 0.21^d

4.49 ± 0.29^c

6.19 ± 0.24^d

9.90 ± 0.52^e

0.78 ± 0.09^a

Total³

1.69 ± 0.11^a

11.1 ± 0.46^b

13.9 ± 0.54^c

19.8 ± 0.53^d

20.0 ± 0.83^d

0.78 ± 0.09^a

liver

EPA

ND^a

4.90 ± 0.39^b

9.68 ± 0.46^c

8.29 ± 0.83^c

5.77 ± 0.52^b

ND^a

DPA

0.11 ± 0.00^a

1.58 ± 0.11^b

2.18 ± 0.14^c

3.90 ± 0.45^d

1.84 ± 0.14^b,c

0.12 ± 0.02^a

DHA

1.70 ± 0.17^a

10.9 ± 1.24^b

9.41 ± 0.59^b

14.0 ± 0.57^c

22.0 ± 0.77^d

1.98 ± 0.21^a

Total

1.72 ± 0.18^a

18.8 ± 1.04^b

21.3 ± 0.80^c

26.2 ± 1.19^d

29.6 ± 0.80^e

2.07 ± 0.22^a

epididymal fat pad

EPA

ND^a

0.11 ± 0.01^a

0.20 ± 0.01^a

2.31 ± 0.15^c

1.49 ± 0.18^b

ND^a

DPA

ND^a

0.17 ± 0.01^a

0.28 ± 0.01^b

0.86 ± 0.09^c

0.93 ± 0.07^c

ND^a

DHA

ND^a

0.18 ± 0.02^a

0.16 ± 0.03^a

0.64 ± 0.07^b

2.76 ± 0.23^c

ND^a

Total

ND^a

0.46 ± 0.03^a,b

0.64 ± 0.03^b

3.81 ± 0.28^c

5.17 ± 0.44^d

ND^a

prostate

EPA

ND^a

2.04 ± 0.26^b

3.82 ± 0.41^c

4.33 ± 0.96^c

3.43 ± 0.54^c

ND^a

DPA

ND^a

2.30 ± 0.28^b

4.12 ± 0.30^c

4.14 ± 0.73^c

1.75 ± 0.13^b

ND^a

DHA

2.18 ± 0.10^a

4.80 ± 0.54^b

5.14 ± 0.13^b

7.58 ± 0.63^c

9.93 ± 0.72^d

1.01 ± 0.13^a

Total

2.18 ± 0.10^a

9.15 ± 0.87^b

13.1 ± 0.28^c

16.1 ± 2.18^d

15.1 ± 0.95^c,d

1.01 ± 0.13^a