Table 3 Spearman correlation coefficients for the correlation of 3-indoxyl sulfate and short-chain fatty acid levels with CRP, creatinine, GFR and fecal calprotectin. Analysis was performed using data of all IBD patients, of CD patients and of UC patients. Significant correlations are in bold. * P < 0.05, ** P < 0.01
Marker | 3-Indoxyl Sulfate/Creatinine | Acetate | Propionate | Butyrate | Isobutyrate |
|---|---|---|---|---|---|
Patients with IBD | |||||
CRP | -0.064 | 0.232 | 0.297* | 0.217 | 0.113 |
Creatinine | -0.264 | -0.016 | -0.141 | -0.033 | -0.161 |
GFR | 0.022 | 0.166 | 0.148 | 0.145 | 0.163 |
Fecal calprotectin | 0.162 | 0.137 | 0.118 | 0.094 | 0.082 |
Patients with Crohn´s disease | |||||
CRP | -0.130 | 0.061 | 0.169 | 0.031 | 0.089 |
Creatinine | -0.156 | 0.051 | -0.074 | 0.063 | -0.067 |
GFR | -0.206 | 0.124 | 0.095 | 0.029 | 0.110 |
Fecal calprotectin | 0.151 | -0.006 | -0.052 | -0.151 | -0.043 |
Patients with Ulcerative colitis | |||||
CRP | -0.093 | 0.528* | 0.471* | 0.511* | 0.016 |
Creatinine | -0.414 | -0.089 | -0.220 | -0.087 | -0.120 |
GFR | 0.458 | 0.209 | 0.169 | 0.245 | 0.106 |
Fecal calprotectin | 0.254 | 0.474* | 0.414 | 0.602** | 0.353 |