Fig. 5
From: Ceramide synthase 4 overexpression exerts oncogenic properties in breast cancer
Expression of EMT markers is increased in CerS4-overexpressing MCF-7 cells. (A) Representative western blots of an epithelial marker (E-cadherin) and mesenchymal markers (N-cadherin, vimentin, and Snail) (left) and their densitometric analysis (right) in MCF-7 and MCF-7/CerS4 cells (n = 3). (B) EMT scores in MCF-7 and MCF-7/CerS4 cells (n = 3). (C) Cell migration in MCF-7 and MCF-7/CerS4 cells (n = 3). Two-tailed Student’s t-test was performed. Significance is indicated as follows :*P < 0.05, **P < 0.01