Table 1 Functional annotation of upregulated genes in MCF-7/CerS4 cells using Reactome_2022

Innate Immune System R-HSA-168,249

100 (1035)

1.80E − 12

2.36E-09

Immune System R-HSA-168,256

155 (1943)

7.02E − 12

4.60E-09

Cell Cycle, Mitotic R-HSA-69,278

60 (523)

9.03E − 11

3.94E-08

Mitotic G1 Phase and G1/S Transition R-HSA-453,279

28 (147)

1.55E − 10

5.09E-08

Cell Cycle R-HSA-1,640,170

68 (654)

3.77E − 10

9.87E-08

Interleukin-4 and Interleukin-13 Signaling R-HSA-6,785,807

23 (107)

5.57E − 10

1.22E-07

G1/S Transition R-HSA-69,206

25 (129)

1.02E − 09

1.90E-07

G1/S-Specific Transcription R-HSA-69,205

12 (29)

2.29E − 09

3.75E-07

NGF-Stimulated Transcription R-HSA-9,031,628

13 (39)

1.11E − 08

1.35E-06