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Table 2 Association between LAP, TyG, and VAI quartiles with 5-year incidence CVD odds

From: Evaluation of the novel three lipid indices for predicting five- and ten-year incidence of cardiovascular disease: findings from Kerman coronary artery disease risk factors study (KERCADRS)

Variables

Quartile numbers

CVD cases

Crude OR (95% CI)

Adjusted OR (95% CI)

LAP

Q1 < 14.77

471

45

1.00 (as reference)

1.00 (as reference)

Q2 14.77–31.45

472

80

1.93 (1.31, 2.85)

1.21 (0.80, 1.85)

Q3 31.46–53.89

470

126

3.46 (2.40, 5.01)

1.86 (1.23, 2.81) ‡

Q4 > 53.89

470

147

4.31 (2.99, 6.20)

2.24 (1.44, 3.50) ‡

P for trend

  

< 0.001

< 0.001

OR Per 1 increment

1883

398

1.01 (1.01, 1.01)

1.01 (1.00, 1.01)

TyG

Q1 < 8.21

471

55

1.00 (as reference)

1.00 (as reference)

Q2 8.21–8.61

470

103

2.12 (1.49, 3.03)

1.47 (1.00, 2.16)

Q3 8.62–9.04

473

103

2.11 (1.47, 3.01)

1.25 (0.84, 1.86)

Q4 > 9.04

468

137

3.13 (2.22, 4.42)

1.57 (1.02, 2.42) †

P for trend

  

< 0.001

< 0.126

OR Per 1 increment

1882

398

1.77 (1.49, 2.12)

1.30 (1.00, 1.70)

VAI

Q1 < 1.35

470

64

1.00 (as reference)

1.00 (as reference)

Q2 1.35–2.08

470

95

1.61 (1.14, 2.27)

1.28 (0.88, 1.86)

Q3 2.09–3.39

470

105

1.82 (1.30, 2.57)

1.27 (0.88, 1.84)

Q4 > 3.39

470

133

2.50 (1.80, 3.49)

1.58 (1.08, 2.33) †

P for trend

  

< 0.001

0.03

OR Per 1 increment

1880

397

1.05 (1.01, 1.09)

1.06 (0.99, 1.13)

  1. LAP, lipid accumulation product; TyG, triglyceride glucose index; VAI, visceral adiposity index; OR, odds ratio; CI, confidence interval; Q, quartile
  2. Crude: Not adjusted for any variables
  3. Adjusted: for age, sex, job, education, physical activity, smoking, total cholesterol, blood pressure, and LDL
  4. P values are calculated using multivariable logistic regression
  5. Significant level of † P < 0.05 and ‡ P < 0.01