Evaluation of the novel three lipid indices for predicting five- and ten-year incidence of cardiovascular disease: findings from Kerman coronary artery disease risk factors study (KERCADRS)

Table 6 Diagnostic performance of LAP, TyG, and VAI in detecting CVD

Total	AUC (95% CI)	Cut-off	Sensitivity	Specificity	Youden index
5-year incidence
WC	0.655 (0.624, 0.685)	90	47	76	0.232
LAP	0.644 (0.615, 0.673)	34.38	65	60	0.249
BMI	0.617 (0.586, 0.647)	24.83	69	50	0.188
TyG	0.608 (0.578, 0.639)	8.47	74	44	0.174
VAI	0.591 (0.561, 0.622)	2.36	54	60	0.143
TG	0.587 (0.557, 0.618)	95	78	37	0.145
FBS	0.577 (0.544, 0.610)	102	33	79	0.123
TC	0.571 (0.539, 0.603)	174	74	40	0.133
LDL	0.561 (0.529, 0.505)	122	60	51	0.112
HDL	0.470 (0.437, 0.503)	20	99	02	0.004
10-year incidence
LAP	0.651 (0.622, 0.681)	28.21	71	53	0.249
WC	0.649 (0.619, 0.679)	81	72	51	0.232
BMI	0.633 (0.602, 0.663)	25.35	64	56	0.209
TyG	0.617 (0.586, 0.626)	8.99	40	79	0.196
TC	0.612 (0.581, 0.642)	174	77	42	0.195
TG	0.605 (0.573, 0.636)	99	75	41	0.159
LDL	0.595 (0.564, 0.626)	114.2	74	44	0.179
VAI	0.595 (0.563, 0.626)	2.63	48	69	0.170
FBS	0.593 (0.561, 0.625)	97	43	72	0.149
HDL	0.487 (0.455, 0.519)	37	52	49	0.007

AUC, area under curve; BMI, body mass index; CVD, cardiovascular disease; FBS, fasting blood sugar; HDL, high-density lipoprotein; LAP, lipid accumulation product; LDL, low-density lipoprotein; TC, total cholesterol; TG, triglyceride; TyG, triglyceride-glucose index; VAI, visceral adiposity index, WC, waist circumference

ISSN: 1476-511X