Table 1 Clinical characteristics between baseline and follow-up
From: Persistent dyslipidemia increases the longitudinal changes in telomere length
Total population (n = 1624) | Healthy persistently (n = 664) | Dyslipidemia in baseline or follow-up (n = 748) | Dyslipidemia persistently (n = 212) | P-value | |
|---|---|---|---|---|---|
ΔRTL | 1.50 ± 2.98 | 1.25 ± 3.32 | 1.62 ± 2.67 | 1.88 ± 2.87 | 0.010 |
RTL in baseline | 1.95 ± 2.50 | 1.87 ± 2.39 | 1.95 ± 2.51 | 2.19 ± 2.80 | 0.274 |
RTL in follow-up | 0.44 ± 1.63 | 0.61 ± 2.34 | 0.33 ± 0.89 | 0.30 ± 0.61 | 0.002 |
Gender (male) | 654(40.3%) | 286(43.1%) | 278(37.2%) | 90(42.5%) | 0.061 |
Baseline | |||||
Age (years) | 47.31 ± 10.56 | 46.82 ± 11.13 | 47.55 ± 10.22 | 47.99 ± 9.82 | 0.261 |
BMI(kg/m2) | 23.57 ± 3.19 | 23.08 ± 3.15 | 23.66 ± 3.16 | 24.68 ± 3.09 | < 0.001 |
WC (cm) | 80.84 ± 9.35 | 79.52 ± 9.35 | 81.42 ± 9.29 | 82.94 ± 9.63 | 0.044 |
HC (cm) | 92.28 ± 5.99 | 91.75 ± 5.84 | 92.32 ± 5.98 | 93.80 ± 6.23 | < 0.001 |
SBP (mmHg) | 123.80 ± 19.09 | 123.34 ± 19.07 | 123.66 ± 18.58 | 125.73 ± 20.86 | 0.276 |
DBP (mmHg) | 79.15 ± 11.30 | 78.16 ± 11.26 | 79.30 ± 10.89 | 81.74 ± 12.44 | < 0.001 |
TC (mmol/L) | 3.93 ± 0.76 | 3.85 ± 0.60 | 3.98 ± 0.71 | 4.00 ± 1.20 | 0.002 |
TG (mmol/L) | 1.33 ± 0.92 | 1.15 ± 0.40 | 1.32 ± 1.06 | 1.94 ± 1.23 | < 0.001 |
HDL-C (mmol/L) | 1.30 ± 0.30 | 1.41 ± 0.25 | 1.29 ± 0.26 | 1.00 ± 0.38 | < 0.001 |
LDL-C (mmol/L) | 2.03 ± 0.62 | 1.93 ± 0.49 | 2.09 ± 0.56 | 2.16 ± 1.01 | < 0.001 |
FBG (mmol/L) | 5.39 ± 1.58 | 5.16 ± 1.77 | 5.46 ± 1.47 | 5.81 ± 1.23 | < 0.001 |
Smoking (yes) | 280(17.2%) | 111(16.7%) | 121(16.2%) | 48(22.6%) | 0.080 |
Alcohol drinking (yes) | 145(8.9%) | 66(9.9%) | 59(7.9%) | 20(9.4%) | 0.387 |
Follow-up | |||||
Age (years) | 57.72 ± 10.21 | 56.51 ± 10.39 | 58.33 ± 10.12 | 59.37 ± 9.55 | < 0.001 |
BMI(kg/m2) | 25.32 ± 5.39 | 24.64 ± 3.55 | 25.63 ± 6.90 | 26.37 ± 3.51 | < 0.001 |
WC (cm) | 87.60 ± 9.91 | 86.60 ± 9.68 | 87.53 ± 9.73 | 90.95 ± 10.59 | < 0.001 |
HC (cm) | 94.92 ± 7.38 | 94.17 ± 5.40 | 95.14 ± 9.12 | 96.48 ± 5.30 | < 0.001 |
SBP (mmHg) | 136.28 ± 20.03 | 136.94 ± 20.28 | 134.88 ± 19.13 | 139.19 ± 21.90 | 0.012 |
DBP (mmHg) | 85.65 ± 13.70 | 86.20 ± 13.32 | 84.92 ± 13.30 | 86.48 ± 16.01 | 0.140 |
TC (mmol/L) | 4.91 ± 0.99 | 4.57 ± 0.77 | 5.14 ± 1.00 | 5.13 ± 1.21 | < 0.001 |
TG (mmol/L) | 1.70 ± 1.11 | 1.20 ± 0.45 | 1.92 ± 1.16 | 2.51 ± 1.57 | < 0.001 |
HDL-C (mmol/L) | 1.75 ± 0.51 | 1.62 ± 0.38 | 1.87 ± 0.60 | 1.80 ± 0.45 | < 0.001 |
LDL-C (mmol/L) | 3.83 ± 1.67 | 2.75 ± 0.59 | 4.57 ± 1.79 | 4.62 ± 1.68 | < 0.001 |
FBG (mmol/L) | 5.81 ± 1.93 | 5.50 ± 1.28 | 5.94 ± 2.22 | 6.32 ± 2.33 | < 0.001 |
Smoking (yes) | 213(13.1%) | 92(13.9%) | 91(12.2%) | 30(14.2%) | 0.574 |
Alcohol drinking (yes) | 212(13.1%) | 91(13.7%) | 96(12.8%) | 25(11.8%) | 0.749 |