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Table 1 Baseline characteristics Stratified by the groups with and without AAAa

From: Association between the non-HDL-cholesterol to HDL- cholesterol ratio and abdominal aortic aneurysm from a Chinese screening program

Variables

Unmatched population

Matched population

Normal (n = 9340)

AAA (n = 219)

SMD

P†

Normal (n = 219)

AAA (n = 219)

SMD

P†

Age (years)

70.3 ± 0.1

72.6 ± 0.4

0.345

< 0.001

72.6 ± 0.5

72.6 ± 0.4

0.004

0.946

BMI (Kg/m2)

23.9 ± 0.03

23.8 ± 0.2

0.043

0.507

24.0 ± 0.2

23.8 ± 0.2

0.098

0.583

Sex (male)

63.7 (5949)

89.0 (195)

0.625

< 0.001

92.2 (202)

89.0 (195)

0.110

0.251

Smoking, %

23.7 (2216)

40.2 (88)

0.358

< 0.001

37.4 (82)

40.2 (88)

0.056

0.556

Hypertension, %

54.0 (5047)

66.7 (146)

0.260

< 0.001

66.2 (145)

66.7(146)

0.010

0.919

Diabetes mellitus, %

21.6 (2013)

18.7 (41)

0.071

0.313

15.1 (33)

18.7 (41)

0.097

0.308

Coronary artery disease, %

38.8 (3627)

56.2 (3750)

0.352

< 0.001

53.0 (116)

56.2 (123)

0.064

0.502

Peripheral artery disease, %

3.3(312)

3.7(8)

0.017

0.799

5.0 (11)

3.7 (8)

0.067

0.482

Stroke, %

5.4(503)

10.0(22)

0.175

0.003

9.6 (21)

10.0 (22)

0.015

0.872

Maximal abdominal aortic diameter (mm)

19.0 (17.0–20.5)

36.0 (32.0–47.0)

2.317

< 0.001

20.0 (18.0–21.0)

36.0 (32.0–47.0)

2.303

< 0.001

ALT (U/L)

20.0 (14.7–27.7)

18.0 (14.0–25.0)

0.060

0.003

21.0 (16.0–27.4)

18.0 (14.0–25.0)

0.214

< 0.001

AST (U/L)

22.0 (18.3–28.0)

21.0 (18.7–27.5)

0.015

0.407

22.9 (19.0–28.4)

21.0 (18.7–27.5)

0.087

0.069

UA (mmol/L)

398.0 (327.9–460.0)

422.0 (368.0–504.3)

0.332

< 0.001

402.0 (351.3–483.3)

422.0 (368.0–504.3)

0.234

0.006

CR (μmol/L)

81.0 (67.0–96.8)

94.9 (77.7–118.3)

0.328

< 0.001

89.2 (75.1–105.0)

94.9 (77.7–118.3)

0.154

0.010

BUN (mmol/L)

5.5 (4.5–6.9)

6.2 (5.2–8.2)

0.320

< 0.001

5.9 (4.6–7.3)

6.2 (5.2–8.2)

0.141

0.106

TG (mmol/L)

1.4 (1.0–1.9)

1.4 (1.0–1.7)

0.087

0.912

1.4 (1.0–1.9)

1.4 (1.0–1.7)

0.039

0.245

TC (mmol/L)

4.6 (3.8–5.4)

4.6 (3.7–5.3)

0.076

0.265

4.1 (3.5–5.2)

4.6 (3.7–5.3)

0.216

0.034

LDL- C (mmol/L)

2.8 (2.2–3.5)

2.9 (2.3–3.5)

0.060

0.250

2.6 (2.0–3.3)

2.9 (2.3–3.5)

0.293

0.002

HDL-C (mmol/L)

1.1 (1.0–1.4)

1.0 (0.9–1.2)

0.102

 < 0.001

1.1 (0.9–1.3)

1.0 (0.9–1.2)

0.206

0.049

non-HDL-C (mmol/L)

3.4 (2.7–4.2)

3.6 (2.8–4.2)

0.102

0.114

3.1 (2.5–3.9)

3.6 (2.8–4.2)

0.343

0.001

non-HDL-C / HDL-C ratio

2.9 (2.2–3.8)

3.5 (2.9–4.3)

0.457

 < 0.001

3.0 (2.3–3.8)

3.5 (2.9–4.3)

0.449

< 0.001

Fasting glucose (mmol/L)

5.3 (4.7–6.3)

5.2 (4.5–6.6)

0.088

0.109

5.3 (4.6–6.2)

5.2 (4.5–6.6)

0.107

0.197

HBA1C (mmol/L)

6.1 (5.7–6.3)

6.0 (5.6–6.2)

0.273

 < 0.001

6.1 (5.8–6.2)

6.0 (5.6–6.2)

0.236

0.021

Medication use

 Angiotensin system inhibitors, %

47.5 (4439)

56.6 (124)

0.183

0.008

54.3 (119)

56.6 (124)

0.046

0.631

 Beta-blockers, %

42.1 (3932)

62.6 (137)

0.418

< 0.001

58.0 (127)

62.6 (137)

0.093

0.329

 Statins, %

51.0 (4762)

67.1 (147)

0.332

< 0.001

65.8 (144)

147.0 (67.1)

0.029

0.761

 Metformin, %

9.6 (895)

7.8 (17)

0.065

0.365

7.8 (17)

7.8 (17)

< 0.001

1.000

  1. Abbreviations: AAA Abdominal aortic aneurysm, BMI Body mass index, ALT Alanine aminotransferase, AST aspartate aminotransferase, UA Uric acide, Cr Creatinine, BUN Blood urea nitrogen, TG Triglyceride, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, non-HDL-C Non-high-density lipoprotein cholesterol, non-HDL-C/HDL-C ratio Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio, HbA1c Hemoglobin A1c, SMD Standardized mean difference
  2. aValues are given as mean + standard deviation, number (percentage), or median (quartiles 1 through 3). †P-values were derived from Mann–Whitney U-tests for continuous variables, and Chi-square tests for categorical variables
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Lipids in Health and Disease

ISSN: 1476-511X