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Table 1 General characteristics of subjects

From: Shift in prevalence and systemic inflammation levels from NAFLD to MAFLD: a population-based cross-sectional study

 

Overall (n = 6718)

non-MAFLD (n = 4388)

MAFLD (n = 2330)

non-NAFLD (n = 4540)

NAFLD (n = 2178)

Age, years

57.0 (50.0, 65.0)

57.0 (49.0, 65.0)

58.0 (52.0, 66.0)*

57.0 (49.0, 65.0)

58.0 (52.0, 66.0)*

Sex

    

*

 Male

2328 (34.7)

1500 (34.2)

828 (35.6)

1657 (36.5)

671 (30.8)

 Female

4390 (65.4)

2889 (65.8)

1501 (64.5)

2883 (63.5)

1507 (69.2)

Education level

  

*

 

*

 Less than primary school

2268 (33.8)

1441 (32.8)

827 (35.5)

1444 (31.8)

824 (37.8)

 Primary school

2292 (34.1)

1514 (34.5)

778 (33.4)

1567 (34.5)

725 (33.3)

 Middle school

1555 (23.2)

1049 (23.9)

506 (21.7)

1107 (24.4)

448 (20.6)

 High school or higher

603 (9.0)

385 (8.8)

218 (9.4)

422 (9.3)

181 (8.3)

Occupation

  

*

 

*

 Farmer or unemployment

4878 (72.6)

3208 (71.9)

1754 (73.8)

3233 (71.2)

1645 (75.5)

 Worker

690 (10.3)

502 (11.3)

202 (8.5)

514 (11.3)

176 (8.1)

 Sales or service

417 (6.2)

282 (6.3)

141 (5.9)

293 (6.5)

124 (5.7)

 Official job

663 (9.9)

428 (9.6)

251 (10.6)

451 (9.9)

212 (9.7)

 Other

70 (1.0)

43 (1.0)

28 (1.2)

49 (1.1)

21 (1.0)

Smoking history

    

*

 Never-smoker

4957 (73.8)

3246 (74.0)

1711 (73.5)

3261 (71.8)

1696 (77.9)

 Former smoker

598 (8.9)

373 (8.5)

225 (9.7)

410 (9.0)

188 (8.6)

 Current smoker

1163 (17.3)

770 (17.5)

393 (16.9)

869 (19.1)

294 (13.5)

T2DM

  

*

 

*

 No

5430 (80.8)

3865 (88.1)

1565 (67.2)

3967 (87.4)

1463 (67.2)

 Yes

1288 (19.2)

524 (11.9)

764 (32.8)

573 (12.6)

715 (32.8)

Hypertension

  

*

 

*

 No

3584 (53.4)

2695 (61.4)

889 (38.2)

2720 (59.9)

864 (39.7)

 Yes

3134 (46.7)

1694 (38.6)

1440 (61.8)

1820 (40.1)

1314 (60.3)

BMI, kg/m2

  

*

 

*

 < 18.5

163 (2.4)

162 (3.7)

1 (0)

161 (3.6)

2 (0.1)

 18.5–23.9

3265 (48.6)

2848 (64.9)

417 (17.9)

2837 (62.4)

428 (19.7)

 24.0–27.9

2518 (37.5)

1216 (27.7)

1302 (55.9)

1330 (29.3)

1188 (54.5)

 ≥ 28.0

772 (11.5)

162 (3.7)

610 (26.2)

212 (4.7)

560 (25.7)

WC, cm

82.8 (76.4, 89.2)

79.4 (73.8, 85.1)

89.2 (84.0, 94.8)*

80 (74, 86)

88.8 (83.4, 94.2)*

Hipline, cm

93.8 (89.8, 98.0)

92.0 (88.4, 95.8)

97.2 (93.5, 101.2)*

92.2 (88.6, 96.0)

97.0 (93.2, 101.0)*

SBP, mmHg

131.5 (119.0, 146.5)

128.0 (116.5, 142.5)

138.0 (125.0, 152.0)*

128.5 (117.0, 143.0)

138.0 (124.5, 152.0)*

DBP, mmHg

84.0 (7.07, 91.5)

82.0 (75.5, 89.5)

88.0 (81.0, 95.0)*

82.5 (75.5, 90.0)

87.5 (80.5, 94.5)*

TG, mmol/L

1.1 (0.8, 1.6)

1.0 (0.7, 1.3)

1.5 (1.1, 2.1)*

1.0 (0.8, 1.3)

1.5 (1.1, 2.0)*

HDL-c, mmol/L

1.6 (1.4, 1.8)

1.7 (1.4, 1.9)

1.5 (1.3, 1.7)*

1.6 (1.4, 1.9)

1.5 (1.3, 1.7)*

FBG, mmol/L

5.0 (4.6, 5.5)

4.8 (4.5, 5.3)

5.2 (4.8, 6.1)*

4.9 (4.5, 5.3)

5.2 (4.8, 6.1)*

2 h PG, mmol/L

7.3 (6.0, 9.0)

6.9 (5.8, 8.4)

8.2 (6.7, 10.4)*

6.9 (5.8, 8.4)

8.2 (6.7, 10.4)*

FINs

7.1 (4.9, 10.3)

5.9 (4.2, 8.3)

10.1 (7.2, 13.6)*

6.0 (4.3, 8.4)

10.0 (7.2, 13.4)*

ALT, U/L

19.0 (15.0, 26.0)

18.0 (14.0, 23.0)

23.0 (18.0, 31.0)*

18.0 (14.0, 24.0)

23.0 (18.0, 31.0)*

AST, U/L

22.0 (18.0, 26.0)

21.0 (18.0, 25.0)

22.0 (19.0, 27.0)*

22.0 (18.0, 26.0)

22.0 (19.0, 26.0)

  1. Data are presented as median with the interquartile range [M (P25-P75)], or frequency (percentage) [n (%)]
  2. MAFLD metabolic associated fatty liver disease, NAFLD nonalcoholic fatty liver disease, T2DM type 2 diabetes mellitus, WC waist circumference, BMI body mass index, SBP systolic blood pressure, DBP diastolic pressure, TG triglyceride, HDL-C high-density lipoprotein cholesterol, FBG fasting blood glucose, 2 h PG 2-h post-load blood glucose, FINs Fasting insulin, ALT alanine aminotransferase, AST aspartate aminotransferase
  3. *P < 0.05 between the non-MAFLD and MAFLD, and non-NAFLD and NAFLD calculated by Wilcoxon Signed Rank Test or Chi-squared test
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Lipids in Health and Disease

ISSN: 1476-511X