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Table 4 Evaluation of inflammatory status of MAFLD with and without CRP

From: Shift in prevalence and systemic inflammation levels from NAFLD to MAFLD: a population-based cross-sectional study

Indicators

Overall (n = 6718)

Non-MAFLDa (n = 4388)

MAFLDa (n = 2330)

Non-MAFLDb (n = 4398)

MAFLDb (n = 2320)

CRP, mg/L

1.11 (0.73, 2.04)

1.00 (0.68, 1.74)

1.39 (0.87, 2.50)*

1.00 (0.68, 1.75)

1.39 (0.87, 2.50)+

WBC, 10^9/L

5.74 (4.90, 6.78)

5.52 (4.72, 6.55)

6.11 (5.32, 7.11)*

5.52 (4.72, 6.55)

6.11 (5.32, 7.11)+

LYMPH, 10^9/L

2.01 (1.65, 2.43)

1.92 (1.58, 2.32)

2.17 (1.81, 2.60)*

1.92 (1.58, 2.32)

2.18 (1.81, 2.61)+

NEUT, 10^9/L

3.17 (2.56, 3.96)

3.05 (2.47, 3.83)

3.36 (2.78, 4.14)*

3.05 (2.47, 3.84)

3.36 (2.78, 4.14)+

MONO, 10^9/L

0.34 (0.27, 0.41)

0.33 (0.27, 0.40)

0.35 (0.29, 0.43)*

0.33 (0.27, 0.41)

0.35 (0.29, 0.43)+

MPV, fL

10.60 (10.00, 11.20)

10.60 (10.00, 11.20)

10.50 (10.00, 11.10)

10.60 (10.00, 11.20)

10.50 (10.00, 11.10)

ALB, g/L

48.80 (47.00, 50.60)

48.70 (46.90, 50.50)

49.00 (47.30, 50.80)*

48.70 (46.90, 50.50)

48.95 (47.30, 50.75)+

NLR

1.57 (1.22, 2.04)

1.60 (1.22, 2.07)

1.53 (1.22, 1.96)*

1.60 (1.22, 2.07)

1.53 (1.22, 1.96)+

d_NLR

1.27 (1.00, 1.61)

1.28 (1.00, 1.62)

1.24 (1.00, 1.57)

1.28 (1.00, 1.62)

1.24 (1.00, 1.57)+

PLR

121.43 (97.95, 150.53)

125.46 (100.00, 156.1)

114.98 (93.91, 142.00)*

125.55 (100.00, 156.10)

114.98 (93.78, 141.97)+

SII

382.53 (284.17, 521.14)

380.66 (278.16, 524.12)

386.62 (293.20, 517.52)

380.67 (278.21, 524.78)

386.46 (292.91, 517.18)

SIRI

0.53 (0.37, 0.75)

0.52 (0.36, 0.75)

0.55 (0.39, 0.76)*

0.52 (0.36, 0.75)

0.55 (0.39, 0.76)+

LMR

5.99 (4.78, 7.43)

5.88 (4.68, 7.31)

6.21 (5.05, 7.57)*

5.88 (4.68, 7.30)

6.21 (5.05, 7.57)+

ALI

740.39 (562.69, 974.88)

696.1 (528.42, 915.45)

839.78 (646.5, 1072.40)*

696.01 (528.37, 915.36)

840.86 (648.4, 1073.14)+

CA

0.02 (0.01, 0.04)

0.02 (0.01, 0.04)

0.03 (0.02, 0.05)*

0.02 (0.01, 0.04)

0.03 (0.02, 0.05)+

  1. Data are presented as median with the interquartile range [M (P25-P75)]
  2. CRP C-reactive protein, WBC white blood cell, LYMPH lymphocyte, NEUT neutrophils, MONO monocyte, MPV mean platelet volume, ALB albumin, NLR neutrophils-to-lymphocyte ratio, SII systemic immune inflammation index, SIRI systemic immune inflammation response index
  3. aMAFLD fully defined according to the standard
  4. bMAFLD defined after removing CRP from diagnostic criteria
  5. *P < 0.05 for MAFLD and non-MAFLD according to the standard by Wilcoxon Signed Rank test
  6. +P < 0.05 for the comparison of MAFLD and non-MAFLD after removing CRP by Wilcoxon Signed Rank test
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Lipids in Health and Disease

ISSN: 1476-511X