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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: ACT001 Alleviates chronic kidney injury induced by a high-fat diet in mice through the GPR43/AMPK pathway

Fig. 6

ACT001 reduce renal inflammation and oxide stress in ORG mice. (A) Western blot results of p-p65, IKKβ, NLRP3, NRF2, Keap 1 (B) p-p65 greyscale semi-quantitative analysis (C) IKKβgreyscale semi-quantitative analysis (D NLRP3 greyscale semi-quantitative analysis (E) TNF-a mRNA level (F) IL-6 mRNA level (G) ROS immunofluorescence image (40 ×) (H) ROS fluorescence intensity measurement (I) NRF2 greyscale semi-quantitative analysis (J) Keap1 semi-quantitative analysis (K) F4/80 immunofluorescence image (40 ×) (L) Quantitative measurement of F4/80 fluorescence intensity (M) INOS immunohistochemistry image (40 ×) (N) INOS positive regions quantitative analysis *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. ND; #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001 vs HFD

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Lipids in Health and Disease

ISSN: 1476-511X