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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: ACT001 Alleviates chronic kidney injury induced by a high-fat diet in mice through the GPR43/AMPK pathway

Fig. 7

The effect of ACT001 on the colonic barrier. (A) Colon macroscopy (B) Colon length comparison (C) Colon HE staining (40 ×), immunohistochemical ZO-1 (40 ×), occluding (40 ×), GPR43 (40 ×), NLRP3 (40 ×) (D) ZO-1 positive area quantitative analysis (E) Occludin positive area *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. ND; #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001 vs HFD

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