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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Role of lipins in cardiovascular diseases

Fig. 1

Schematic of the structure and function of lipins. NLS: nuclear localization signal; PBD: polybasic domain; N-LIP: amino-terminal lipin; C-LIP: carboxy-terminal lipin; M-LIP: middle lipin; PAP: phosphatidate phosphatase; G3P: glycerol 3-phosphate; GPAT: glycerol phosphate acyltransferase; LPA: lyso-phosphatidic acid; PA: phosphatidic acid; LPAAT: lyso-PA-acyltransferase; PLA: phospholipase A; DAG: diacylglycerol; DGAT: diacylglycerol acyltransferase; TAG: triacylglycerol; PC: phosphatidylcholine; PE: phosphatidylethanolamine; PS: phosphatidylserine; DGK: diacylglycerol-kinases; CDP-DAG: cytidine diphosphate diacylglycerol; CDS: CDP-DAG synthase; PI: phosphatidylinositol; PG: phosphatidylglycerol; CL: cardiolipin; and TFs: transcription factors

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Lipids in Health and Disease

ISSN: 1476-511X