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Table 1 Summary of GWAS datasets included in this study

From: Genetically predicted triglycerides mediate the relationship between type 2 diabetes Mellitus and intervertebral disc degeneration

Phenotype

Sample size (case/control)

Number of SNPs

Population

Units

Databases

Exposure

     

Type 2 diabetes (ebi-a-GCST006867)

655,666 (61,714/1,178)

5,030,727

European

logOR

EBI database

Mediation

     

Triglycerides (ieu-b-111)

441,016

12,321,875

European

Not applicable

UKB database

Outcome

     

Intervertebral disc degeneration (finn-b-M13_INTERVERTEB)

184,683 (20,001/164,682)

16,380,337

European

Not applicable

FinnGen database

  1. SNP, single nucleotide polymorphism; Name of data set: ebi-a-GCST006867, ieu-b-111, finn-b-M13_INTERVERTEB