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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes

Fig. 3

Transcriptomics data analysis. A PCA analysis plot. The horizontal and vertical coordinates represent the top two principal components and their contribution to the sample ranking. B Volcano plot of DEGs. C Results of GO enrichment of DEGs. D Results of KEGG enrichment of DEGs. E Demonstration of DEGs in the ECM-receptor interaction pathway. KO nodes with upregulated genes are shown in red, and KO nodes with downregulated genes are shown in green. F Heat map of DEGs associated with fibrosis. G Heat map of DEGs associated with inflammation

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