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Table 3 Metabolic pathways of 27 DEMs in metabolomics analysis

From: A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes

Pathway

Total

Hits

Raw p

-Ln(p)

Holm adjust

FDR

Impact

Hits Cpd

Sphingolipid metabolism

21

2

0.027361

3.5986

1

1

0.04868

Sphingosine; Phytosphingosine

Riboflavin metabolism

4

1

0.049469

3.0064

1

1

0.5

Riboflavin

Nicotinate and nicotinamide metabolism

15

1

0.17383

1.7497

1

1

0.1943

Nicotinamide

Steroid hormone biosynthesis

77

2

0.25244

1.3766

1

1

0.05551

Androsterone; Estrone

Lysine degradation

25

1

0.27337

1.2969

1

1

0

L-Hydroxylysine

Biosynthesis of unsaturated fatty acids

36

1

0.36971

0.99505

1

1

0

(9Z)-Octadecenoic acid

Glycerophospholipid metabolism

36

1

0.36971

0.99505

1

1

0.01736

1-Acyl-sn-glycero-3-phosphocholine

Arginine and proline metabolism

38

1

0.38587

0.95227

1

1

0.02346

N-Acetylputrescine

Sphingolipid signaling pathway

15

1

0.17383

1.7497

1

1

0

Sphingosine