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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation

Fig. 2

Puerarin ameliorates pathological alterations, oxidative stress, and iron overload in MAFLD mice. (A) HE staining, Masson staining, and Sirius red staining in control and MAFLD mice treated with vehicle or puerarin. Scale Bar, 100 μm. (B) Assessment of mitochondrial morphology in hepatocytes by TEM. Scale Bar, 0.6 μm. (C) Representative images of DHE staining in mouse liver sections. Scale Bar, 20 μm. (D-G). Measurement of malondialdehyde (MDA), glutathione peroxidase (GSH-Px), catalase (CAT), and superoxide dismutase (SOD) levels in liver tissue in the four groups. (H-I). Measurement of iron concentrations and Fe2+ levels in the livers of mice. The data are expressed as the mean ± SD (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X