Table 3 DEGs of SM metabolism pathway in PF cells
Cell Type | AT2 | Fibroblast | Macrophage | Endothelium | ||||
|---|---|---|---|---|---|---|---|---|
Significance | Fold Change | P value | Fold Change | P value | Fold Change | P value | Fold Change | P value |
SGMS1 | / | / | / | / | −0.18 (IM) | 8.54 E-46 | / | / |
0.06 (AM) | 1.66 E-03 | |||||||
SGMS2 | 0.49 | 1.06 E-24 | / | / | 0.40 (IM) | 2.25 E-176 | / | / |
0.29 (AM) | 7.56 E-117 | |||||||
SMPD1 | / | / | / | / | −0.29 (AM) | 2.54 E-09 | −0.49 | 7.33 E-08 |
SMPD4 | / | / | / | / | −0.24 (IM) | 1.87 E-13 | −0.59 | 3.98 E-06 |
−0.37 (AM) | 1.23 E-17 | |||||||
ASAH1 | −0.37 | 6.67 E-121 | / | / | −0.05 (IM) | 4.47 E-13 | −0.36 | 1.86 E-13 |
−0.02 (AM) | 1.62 E-02 | |||||||
ASAH2 | / | / | / | / | −0.81 (AM) | 1.82 E-04 | / | / |
SPHK1 | / | / | / | / | −0.94 (IM) | 2.30 E-301 | 0.23 | 2.84 E-02 |
−0.89 (AM) | 7.96 E-12 | |||||||
SPHK2 | 0.54 | 1.18 E-04 | / | / | / | / | / | / |
S1PR1 | / | / | / | / | 0.82 (AM) | 3.93 E-02 | −0.31 | 1.32 E-30 |
S1PR3 | / | / | / | / | −0.72 (IM) | 4.05 E-08 | / | / |
S1PR4 | 1.00 | 3.73 E-04 | / | / | / | / | −0.66 | 3.74 E-05 |
SGPL1 | 0.74 | 6.80 E-08 | / | / | −0.50 (IM) | 3.67 E-291 | / | / |
−0.11 (AM) | 2.75 E-03 | |||||||