Table 6 DEGs of lipid droplet metabolism in PF cells
Cell Type | AT2 | Fibroblast | Macrophage | Endothelium | ||||
|---|---|---|---|---|---|---|---|---|
Significance | Fold Change | P value | Fold Change | P value | Fold Change | P value | Fold Change | P value |
GPAT3 | −0.72 | 3.40 E-04 | / | / | −0.57 (IM) | 1.01 E-06 | −0.40 | 5.89 E-21 |
−1.15 (AM) | 3.20 E-03 | |||||||
AGPAT4 | 0.79 | 2.46 E-02 | / | / | 0.31 (IM) | 2.47 E-10 | / | / |
AGPAT5 | / | / | / | / | / | / | 0.80 | 5.41 E-09 |
AGPAT3 | 0.47 | 3.33 E-09 | / | / | −0.35 (AM) | 1.50 E-06 | / | / |
AGPAT1 | 0.73 | 2.91 E-12 | / | / | / | / | / | / |
AGPAT2 | −0.35 | 8.81 E-49 | / | / | / | / | / | / |
PNPLA2 | −0.25 | 9.30 E-09 | / | / | −0.40 (IM) | 1.92 E-03 | / | / |
− 0.35 (AM) | 4.01 E-07 | |||||||
LPIN2 | / | / | / | / | −0.50 (AM) | 3.34 E-31 | / | / |
LPIN3 | 1.29 | 8.21 E-16 | / | / | / | / | / | / |
MGLL | / | / | / | / | −0.46 (AM) | 3.33 E-15 | 1.07 | 5.22 E-40 |
PLIN2 | / | / | −0.37 (FB) | 2.43 E-03 | −0.40 (IM) | 0.00 E+ 00 | / | / |
−0.36 (AM) | 0.00 E+ 00 | |||||||
PLIN5 | / | / | / | / | −0.49 (IM) | 1.13 E-05 | / | / |
−1.65 (AM) | 3.63 E-02 | |||||||
DGAT1 | 0.84 | 5.96 E-20 | / | / | −0.34 (IM) | 1.01 E-19 | / | / |
DGAT2 | −1.10 | 2.05E-10 | / | / | −1.32 (IM) | 4.56 E-80 | / | / |
−1.75 (AM) | 4.05 E-73 | |||||||