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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Lipid droplet accumulation in Wdr45-deficient cells caused by impairment of chaperone-mediated autophagic degradation of Fasn

Fig. 1

Wdr45 knockout in SN4741 cells. (A) The targeting site and sequence of gRNAs. (B) The Wdr45 knockout cell line transfected with the gRNA1 has one or seven base pair deletions in the two alleles. (C) Base pair deletion resulted in a frame-shift and introduced a premature stop codon. (D) Deletion of Wdr45 in knockout cells was confirmed using western blotting

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Lipids in Health and Disease

ISSN: 1476-511X